Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Elife. 2019 May 2;8:e47221. doi: 10.7554/eLife.47221.
T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.
辅助性 T 细胞摄取氨基酸蛋氨酸来合成新的蛋白质,并提供甲基基团,用于 RNA 和 DNA 的甲基化,从而驱动 T 细胞的增殖和分化。