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Eovist 在儿科患者中的应用:要点与陷阱。

Use of Eovist in Pediatric Patients: Pearls and Pitfalls.

机构信息

Division of Diagnostic Imaging and Radiology; Children's National Health System; Washington, DC.

Division of Diagnostic Imaging and Radiology; Children's National Health System; Washington, DC.

出版信息

Curr Probl Diagn Radiol. 2020 Jul-Aug;49(4):266-274. doi: 10.1067/j.cpradiol.2019.04.001. Epub 2019 Apr 5.

Abstract

Magnetic resonance imaging is excellent at characterizing pediatric hepatobiliary pathology. Noncontrast MRI is helpful due to T2 hyperintensity associated with bile, but contrast enhancement offers additional means of lesional characterization. In particular, hepatocyte-specific contrast agents such as gadoxetate disodium (Eovist) exhibit partial hepatobiliary excretion which may be leveraged in these contexts. In this review, we will discuss gadoxetate disodium usage, including a sample-imaging protocol, and demonstrate applications and limitations in the pediatric population.

摘要

磁共振成像在小儿肝胆病理特征描述方面具有显著优势。由于与胆汁相关的 T2 高亮信号,非对比增强 MRI 检查具有一定帮助,但对比增强检查可以提供额外的病灶特征描述手段。具体而言,具有肝特异性的对比剂如钆塞酸二钠(Eovist)可以经部分肝胆排泄,这在上述情况下具有重要应用价值。在这篇综述中,我们将讨论钆塞酸二钠的使用方法,包括一个典型的成像方案,并演示其在儿科人群中的应用和局限性。

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