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捷克斯洛伐克对当前阳痿概念、其发病机制、诊断及治疗的贡献。

Czechoslovak contribution to current concepts in impotence, its pathogenesis, diagnosis and treatment.

作者信息

Michal V

出版信息

Czech Med. 1987;10(1):29-38.

PMID:3107944
Abstract

Czechoslovak contribution to the current concepts in impotence, its pathogenesis, diagnosis and treatment, consists especially in: the recognition of the haemodynamics of erection. The process involves two stages; in the first one, the arterial bed must deliver to the corpora cavernosa (CC) threshold values of volume and pressure needed for filling and distention of the CC, in the second period, the CC function as a closed system on the hydraulic principle, and contractions of the ischiocavernous muscles increase intracavernous pressure to suprasystolic values, the observation that it is just failure of the haemodynamics of erection that plays an important role in the pathogenesis of impotence in a majority of patients. The development of artificial erection into a real functional examination of the CC enables to differentiate: disorders with normal haemodynamics of erection, those due to insufficient arterial supply, insufficient blockage of venous return, or insufficient and ineffective contractions of the ischiocavernous muscles. the development of the phalloarteriographic technique which allows a precise anatomical diagnosis of the lesions in the afferent arterial bed, providing the basis for the development and indication of a number of reconstructive procedures in the arterial bed supplying the CC. In addition, the examination has also helped to clarify the relationship between erectile disorders, arterial disease and their risk factors. In retrospect, Czechoslovak research into impotence has substantially contributed to the recognition of vasculogenic impotence, to the therapy of arteriogenic erectile disorders and to a basic change in the concepts of the aetiology and pathogenesis of impotence.

摘要

捷克斯洛伐克对当前阳痿概念、其发病机制、诊断和治疗的贡献尤其体现在:对勃起血流动力学的认识。该过程包括两个阶段;在第一阶段,动脉床必须向海绵体输送填充和扩张海绵体所需的体积和压力阈值,在第二阶段,海绵体作为一个基于液压原理的封闭系统,坐骨海绵体肌的收缩将海绵体内压力增加到收缩压以上的值,观察到正是勃起血流动力学的失败在大多数患者阳痿的发病机制中起重要作用。将人工勃起发展成为对海绵体的真正功能检查能够区分:勃起血流动力学正常的疾病、由于动脉供应不足、静脉回流阻塞不足或坐骨海绵体肌收缩不足和无效导致的疾病。阴茎动脉造影技术的发展允许对传入动脉床的病变进行精确的解剖诊断,为在供应海绵体的动脉床中开展一些重建手术提供了发展和指征依据。此外,该检查还有助于阐明勃起功能障碍、动脉疾病及其危险因素之间的关系。回顾过去,捷克斯洛伐克对阳痿的研究对血管性阳痿的认识、动脉源性勃起功能障碍的治疗以及阳痿病因和发病机制概念的根本改变做出了重大贡献。

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