van den Berg Jan Willem, Tabrett Kate, Cheong Edward
Norfolk and Norwich Oesophago-gastric Cancer Centre, Norfolk and Norwich University Hospital, Colney Lane, Norwich, UK.
J Thorac Dis. 2019 Apr;11(Suppl 5):S786-S793. doi: 10.21037/jtd.2019.03.47.
Oesophagectomy is a major complex operation associated with significant morbidity and mortality. Epidural analgesia has long been the gold standard postoperative analgesia but is associated with side-effects like hypotension, epidural haematoma and infection. In an attempt to lower morbidity and enhance recovery postoperatively, we have adopted the use of paravertebral catheter analgesia (PVCA) for patients undergoing totally minimal invasive oesophagectomy (TMIO).
Our objective was to review the current literature about the use of both PVCA and epidural analgesia. In addition, we evaluated the effect of PVCA in a large group of patients undergoing TMIO for cancer. We reviewed the records of 100 consecutive patients who had a TMIO with PVCA, spinal morphine, and PCA. Prospective independent scoring of postoperative pain, length of stay, high-dependency unit (HDU) stay, PVCA failure, the use of patient-controlled analgesia (PCA), and the use of vasoconstrictor medication postoperatively was analysed.
One hundred consecutive patients received PVCA with PCA after the TMIO. Catheter related failures occurred in 4 cases. The median pain score over each of the 5 days were 0. The average pain score was highest in the first 24 hours and decreased over the next 4 days postoperatively. The use of PCA was highest in the first 2 days and reduced daily over the subsequent 3 days. Seven patients required rescue analgesia in the form of intercostal nerve (ICN) block. Spinal morphine was successful in 94% of cases. Vasoconstrictors were required in 19% on day 1 and 3% on day 2, postoperatively.
Intraoperative placement of PVCA results in good postoperative pain control after a TMIO. This technique is simple, safe, reproducible and with very low failure rates. Therefore, it should be used instead of epidural catheter analgesia.
食管切除术是一项复杂的大型手术,伴有较高的发病率和死亡率。硬膜外镇痛长期以来一直是术后镇痛的金标准,但会出现低血压、硬膜外血肿和感染等副作用。为了降低发病率并促进术后恢复,我们对接受完全微创食管切除术(TMIO)的患者采用了椎旁导管镇痛(PVCA)。
我们的目的是回顾当前关于PVCA和硬膜外镇痛使用情况的文献。此外,我们评估了PVCA在一大组接受TMIO治疗癌症患者中的效果。我们回顾了100例连续接受TMIO并采用PVCA、脊髓吗啡和PCA的患者的记录。对术后疼痛、住院时间、高依赖病房(HDU)住院时间、PVCA失败情况、患者自控镇痛(PCA)的使用以及术后血管收缩药物的使用进行了前瞻性独立评分分析。
100例连续患者在TMIO后接受了PVCA联合PCA。导管相关失败发生4例。术后5天中每天的中位疼痛评分为0。平均疼痛评分在术后头24小时最高,随后4天逐渐降低。PCA的使用在前2天最高,随后3天每日减少。7例患者需要肋间神经(ICN)阻滞形式的补救镇痛。脊髓吗啡在94%的病例中有效。术后第1天19%的患者和第2天3%的患者需要使用血管收缩剂。
TMIO术中放置PVCA可实现良好的术后疼痛控制。该技术简单、安全、可重复且失败率极低。因此,应使用该技术替代硬膜外导管镇痛。