多发性骨髓瘤患者脂肪来源干细胞中成骨分化的系统性功能障碍。
Systemic Dysfunction of Osteoblast Differentiation in Adipose-Derived Stem Cells from Patients with Multiple Myeloma.
机构信息
Sorbonne Université, INSERM, UMR_S 938, Centre de Recherche Saint-Antoine-Team Genetic and acquired lipodystrophies, Institut Hospitalo-Universitaire de Cardiométabolisme et Nutrition (ICAN), F-75012 Paris, France.
orbonne Université, INSERM, UMR_S 938, Centre de Recherche Saint-Antoine-Team Proliferation and Differentiation of Stem Cells, Institut Universitaire de Cancérologie, F-75012 Paris, France.
出版信息
Cells. 2019 May 10;8(5):441. doi: 10.3390/cells8050441.
Abstract
multiple myeloma; bone disease; osteogenesis; adipogenesis; adipose-derived stem cells; bone marrow; senescence; Dickkopf-related protein 1; systemic disease.
摘要
多发性骨髓瘤；骨病；成骨；成脂；脂肪来源干细胞；骨髓；衰老；Dickkopf 相关蛋白 1；系统性疾病。
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