Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
J Clin Neurosci. 2019 Sep;67:172-177. doi: 10.1016/j.jocn.2019.04.025. Epub 2019 May 11.
Intracranial dermoids (ID) are relatively uncommon. They are usually located in the midline or posterior fossa, and present in the first three decades of life. Rupture of IDs are a rare occurrence, and can present with diverse clinical features. They have a characteristic appearance on Computerized Tomography (CT) and Magnetic-Resonance-Imaging (MRI). Here we retrospectively review the clinical features, radiology, treatment and outcomes of ruptured IDs managed in our institute. We did a retrospective review of all the IDs from 2011 to 2017 that presented to us with rupture, or that were diagnosed to have ruptured based on imaging characteristics. Nine patients qualified for our study. The data of all 9 patients was analyzed retrospectively and their demographic details, clinical variations, and radiological features were studied and analyzed. Mode of management and outcome was assessed. Mean age of the patients was 32.1 years (SD 7.65) with male-female ratio of 7:2. Patients presented with either headache or seizures in the majority. Two patients had hydrocephalus requiring shunts. Despite their varied location and clinical features, all lesions showed similar and characteristic radiological features-namely, fat droplets in subarachnoid spaces, hypo-intensity on Susceptibility-Weighted-Imaging (SWI) with chemical shift artifact. Treatment of patients varied from medical management in 4, to cerebrospinal fluid (CSF) diversion in 2 and surgery for the lesion in 3 cases. Ruptured IDs present with a wide array of clinical features. Imaging characteristics are fairly distinct and consistent, which aids in diagnosis. Decision for mode of management has to be decided based on case-by-case basis.
颅内皮样囊肿(ID)相对少见。它们通常位于中线或后颅窝,发生于生命的头三十年。ID 破裂较为罕见,临床表现多样。它们在计算机断层扫描(CT)和磁共振成像(MRI)上具有特征性表现。在此,我们回顾性分析了我院收治的破裂 ID 的临床特征、影像学、治疗方法和转归。我们回顾性分析了 2011 年至 2017 年间所有因破裂就诊或根据影像学特征诊断为破裂的 ID 患者。9 例患者符合我们的研究标准。对这 9 例患者的数据进行了回顾性分析,研究和分析了他们的人口统计学细节、临床表现和影像学特征。评估了治疗方法和转归。患者的平均年龄为 32.1 岁(标准差 7.65),男女比例为 7:2。大多数患者表现为头痛或癫痫。2 例患者因脑积水需行分流术。尽管病变位置和临床表现各异,但所有病变均表现出相似且特征性的影像学特征,即蛛网膜下腔脂肪滴、磁敏感加权成像(SWI)上低信号伴化学位移伪影。患者的治疗方法从 4 例药物治疗到 2 例脑脊液(CSF)分流术再到 3 例手术治疗不等。破裂的 ID 表现出广泛的临床表现。影像学特征相当独特且一致,有助于诊断。治疗方式的选择必须根据具体情况决定。