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沙特阿拉伯老年患者多重用药的综合概述。

A Comprehensive Overview of Polypharmacy in Elderly Patients in Saudi Arabia.

作者信息

Alsuwaidan Aseel, Almedlej Norah, Alsabti Sawsan, Daftardar Omamah, Al Deaji Fawzi, Al Amri Ali, Alsuwaidan Salem

机构信息

College of Pharmacy, Princes Nourah University, Riyadh KSA 84428, Saudi Arabia.

Pharmacist Consultant in Prince Sultan Military Medical Center, Riyadh KSA 84428, Saudi Arabia.

出版信息

Geriatrics (Basel). 2019 May 15;4(2):36. doi: 10.3390/geriatrics4020036.

Abstract

Saudi Arabia has a great percentage of geriatric patients associated with multiple chronic diseases who require close attention and monitoring for their medications. The purpose of this study is to develop a full-framed picture about the utilization of medications for geriatric patients and how to provide better health-care management. A retrospective cross-sectional study targeting patients 65 years of age and older, who are taking multiple chronic medications for different indications. Descriptive analysis and frequency of the main variables were used as appropriate. Only qualified and professional candidates were chosen for data entry to present the quality and accuracy of data. A total of 3009 patient profiles were analyzed, with the patients' average age in years being 73.26 ± 6.6 (SD). It was found that 55% of the patients have polypharmacy. An average of 6.4 medications were prescribed for patients aged between 65 and 70 years compared with a significant difference for patients aged 71 years and above, while a linear correlation between age and comorbidity diseases associated with all elderly patients. Hypertension, hyperlipidemia, and diabetes mellitus are the most common comorbidity diseases for elderly patients aged 65 years and older. Polypharmacy in geriatrics is defined as a patient aged 65 years and older receiving five or more appropriate medications. It is the responsibility of health-care professionals to reduce the number of medications in elderly patients. Awareness of geriatric medications and diagnosed diseases will improve managing adverse drug reaction and other risk factors. Awareness of geriatric medications should elaborate on how to avoid adverse drug reaction and other risk factors. It is the responsibility of physicians and pharmacists to reduce the number of medications in elderly patients. We also prove that the number of medications will not necessarily increase with age. The main impact of this study is to follow the main recommendations to improve health care management in geriatrics.

摘要

沙特阿拉伯有很大比例的老年患者患有多种慢性疾病,这些患者的用药需要密切关注和监测。本研究的目的是全面了解老年患者的用药情况以及如何提供更好的医疗保健管理。这是一项回顾性横断面研究,目标是65岁及以上正在服用多种用于不同适应症的慢性药物的患者。对主要变量进行了适当的描述性分析和频率统计。仅选择合格且专业的人员进行数据录入,以确保数据的质量和准确性。共分析了3009份患者资料,患者的平均年龄为73.26±6.6(标准差)岁。结果发现,55%的患者存在多重用药情况。65至70岁患者平均开具6.4种药物,71岁及以上患者有显著差异,且所有老年患者的年龄与合并症之间存在线性相关性。高血压、高脂血症和糖尿病是65岁及以上老年患者最常见的合并症。老年医学中的多重用药定义为65岁及以上的患者接受五种或更多适当的药物治疗。减少老年患者的用药数量是医疗保健专业人员的责任。了解老年用药和已诊断疾病将有助于改善药物不良反应及其他风险因素的管理。对老年用药的了解应详细说明如何避免药物不良反应及其他风险因素。减少老年患者的用药数量是医生和药剂师的责任。我们还证明,用药数量不一定会随着年龄增长而增加。本研究的主要影响是遵循主要建议以改善老年医学中的医疗保健管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/6631642/b1ebdc80eea4/geriatrics-04-00036-g001.jpg

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