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中国农业地区慢性精神分裂症患者自杀未遂的发生率及独立人口学和临床相关因素。

The Prevalence of Suicide Attempts and Independent Demographic and Clinical Correlates among Chronic Schizophrenia Patients in Agricultural Areas of China.

机构信息

Department of Psychiatry, Chaohu Hospital of Anhui Medical University, 64 Chaohu North Road, Hefei, Anhui Province, China.

Anhui Psychiatric Center, Anhui Medical University, Anhui Province, China.

出版信息

Psychiatr Q. 2019 Dec;90(4):683-691. doi: 10.1007/s11126-019-09644-1.

Abstract

This study investigated the lifetime prevalence of suicide attempts (SA) and independent demographic and clinical correlates in stabilized schizophrenia inpatients. A cross-sectional study was conducted in three psychiatric hospitals in Anhui province, an agricultural province located in east China. Psychopathology and depressive symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS) and Hamilton Depression Rating Scale (HAMD), respectively. A total of 315 stable schizophrenia inpatients were interviewed prior to discharge. The lifetime prevalence of SA was 22.2%. Multiple logistic regression analysis revealed that female gender (P < 0.001, OR = 3.4, 95%CI: 1.9-6.0), being married (P = 0.02, OR = 2.2, 95%CI: 1.1-4.4) and having more severe depressive symptoms (P = 0.014, OR = 1.2, 95%CI: 1.01-1.3) were independently and significantly associated with higher risk of SA. Lifetime SA is common among hospitalized schizophrenia patients living in agricultural areas of China. For suicide prevention, regular assessments, appropriate interventions and clinical management should be integrated into a community-based psychiatric service model for this population.

摘要

本研究调查了稳定期精神分裂症住院患者一生中自杀未遂(SA)的发生率,以及独立的人口统计学和临床相关因素。在中国东部农业省份安徽省的三家精神病院进行了一项横断面研究。使用阳性和阴性症状量表(PANSS)和汉密尔顿抑郁量表(HAMD)分别评估精神病理学和抑郁症状。在出院前对 315 名稳定的精神分裂症住院患者进行了访谈。一生中自杀未遂的发生率为 22.2%。多因素逻辑回归分析显示,女性(P<0.001,OR=3.4,95%CI:1.9-6.0)、已婚(P=0.02,OR=2.2,95%CI:1.1-4.4)和抑郁症状更严重(P=0.014,OR=1.2,95%CI:1.01-1.3)与自杀未遂风险增加独立相关。在中国农村地区,住院精神分裂症患者一生中自杀未遂的情况较为常见。为了预防自杀,应将定期评估、适当干预和临床管理纳入针对该人群的社区为基础的精神卫生服务模式。

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