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男性尿道“迷你吊带”的初步结果:一种改良的 Andrianne 迷你-Jupette 手术方法,结合阴茎假体植入治疗绝经后女性的尿失禁和轻度压力性尿失禁。

Preliminary Outcomes of the Male Urethral "Mini-Sling": A Modified Approach to the Andrianne Mini-Jupette Procedure With Penile Prosthesis Placement for Climacturia and Mild Stress Urinary Incontinence.

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai Hospital, New York City, NY, USA.

Division of Urology, Rush University Medical Center, Chicago, IL, USA.

出版信息

J Sex Med. 2019 Aug;16(8):1310-1317. doi: 10.1016/j.jsxm.2019.04.009. Epub 2019 May 17.

Abstract

INTRODUCTION

Previous worked showed that the Andrianne Mini-Jupette (AMJ) procedure with inflatable penile prosthesis (IPP) significantly improves climacturia or stress urinary incontinence (SUI) that may accompany erectile dysfunction (ED) after radical prostatectomy. However, with the AMJ procedure, the graft is incorporated into the medial aspect of the corporotomy, thereby requiring a more complex closure. Moreover, in the original report, multiple graft materials were used.

AIM

To describe our technique for "male urethral mini-sling" (MUMS) with a Virtue sling mesh, which is a modified approach to the AMJ, and to assess early postoperative outcomes.

METHODS

A retrospective chart review was performed for men who underwent IPP and MUMS placement with a modified Virtue mesh by 2 high-volume prosthetic urologic surgeons using the same technique. After proximal urethral exposure, the MUMS is sutured to the latera corpora over the bulbar urethra, proximal to and separate from the planned corporotomy, with care taken to avoid excessive urethral tension. The IPP is then placed in standard fashion. Changes in patient-reported climacturia and pads per day for SUI were assessed before and after surgery.

RESULTS

36 men underwent both IPP and MUMS placement between January 2016-October 2018. Mean patient age was 68 years. Etiology for ED and urinary symptoms was prostatectomy alone in 30 of 36 (83%) and prostatectomy plus radiation in 6 of 36 (17%). Preoperative urinary symptoms included climacturia in 30 of 36 (83%) and SUI in 27 of 36 (75%). Mean (SD) follow-up was 5.9 (3.7) months. Climacturia resolved in 28 of 30 (93%), and SUI improved in 23 of 27 (85%). The mean (SD) number of pads per day for those patients with SUI decreased significantly from 1.4 (1.1) before surgery to 0.4 (0.6) after surgery (P = .02). 1 patient required MUMS explantation for urethral erosion after prolonged postoperative catheterization.

CLINICAL IMPLICATIONS

The MUMS with modified Virtue mesh at the time of IPP placement can be used to treat ED with climacturia or mild SUI after radical prostatectomy.

STRENGTHS & LIMITATIONS: Strengths include the use of a consistent operative technique with a single graft material by 2 experienced prosthetic urologic surgeons. Limitations include the retrospective study design, use of subjective postoperative outcomes, lack of comparison group, and relatively moderate follow-up duration.

CONCLUSIONS

Our early results suggest that the MUMS significantly improves bothersome climacturia and mild SUI in addition to treating ED, with little added morbidity. Although further study, including longer-term follow-up, is needed, this approach may be considered in the appropriately counseled patient. Valenzuela RJ, Ziegelmann MJ, Hillelsohn JH, et al. Preliminary Outcomes of the Male Urethral "Mini-Sling": A Modified Approach to the Andrianne Mini-Jupette Procedure With Penile Prosthesis Placement for Climacturia and Mild Stress Urinary Incontinence. J Sex Med 2019;16:1310-1317.

摘要

介绍

之前的研究表明,安德里亚迷你裙(AMJ)手术联合可膨胀阴茎假体(IPP)可显著改善根治性前列腺切除术后可能伴发的勃起功能障碍(ED)相关的尿失禁(尿失禁)或压力性尿失禁(SUI)。然而,采用 AMJ 手术时,移植物被整合到切开部位的内侧,因此需要更复杂的缝合。此外,在最初的报告中,使用了多种移植物材料。

目的

描述我们使用 Virtue 吊带网片进行“男性尿道吊带(MUMS)”的技术,这是对 AMJ 的一种改良方法,并评估早期术后结果。

方法

对 2 名高容量假体泌尿科医生使用相同技术进行 IPP 和 MUMS 联合植入改良 Virtue 网片的患者进行回顾性图表审查。近端尿道暴露后,MUMS 缝合到球部尿道的外侧,靠近并分开计划切开部位,注意避免过度尿道张力。然后放置 IPP。术前和术后评估患者报告的尿失禁相关的尿失禁和每天使用的尿垫数量。

结果

2016 年 1 月至 2018 年 10 月期间,36 名男性接受了 IPP 和 MUMS 联合植入术。患者平均年龄为 68 岁。36 名患者中,ED 和尿失禁的病因分别为单纯前列腺切除术 30 例(83%)和前列腺切除术加放疗 6 例(17%)。术前尿失禁症状包括 30 例(83%)的尿失禁和 27 例(75%)的压力性尿失禁。平均(SD)随访时间为 5.9(3.7)个月。30 例(93%)患者的尿失禁得到缓解,27 例(85%)患者的尿失禁得到改善。那些患有压力性尿失禁的患者每天使用尿垫的数量从术前的 1.4(1.1)显著减少到术后的 0.4(0.6)(P=0.02)。1 例患者因术后长时间留置导尿管出现 MUMS 移植物尿道侵蚀,需要 MUMS 取出。

临床意义

在 IPP 植入时使用改良 Virtue 网片的 MUMS 可用于治疗根治性前列腺切除术后勃起功能障碍相关的尿失禁或轻度尿失禁。

优势和局限性

优势包括 2 名经验丰富的假体泌尿科医生使用一致的手术技术和单一移植物材料。局限性包括回顾性研究设计、使用主观术后结果、缺乏对照组和相对较短的随访时间。

结论

我们的早期结果表明,MUMS 除了治疗 ED 外,还可以显著改善烦人的尿失禁和轻度尿失禁,且并发症很少。尽管需要进一步的研究,包括更长期的随访,但在适当咨询的患者中,可以考虑这种方法。

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