Mortimer Todd, Burzynski Jeff, Kesselman Murray, Vallance Jeff, Hansen Gregory
Section of Pediatric Intensive Care, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.
Faculty of Health Disciplines, Athabasca University, Athabasca, Alberta, Canada.
J Pediatr Intensive Care. 2016 Mar;5(1):28-31. doi: 10.1055/s-0035-1568149. Epub 2015 Nov 18.
This prospective case series documented hypoxemia and potential complications associated with apneic oxygenation in critically ill pediatric patients during rapid sequence intubation. Forty-four patients received apneic oxygenation via nasal cannula at rates of 5, 10, and 15 L/min for ages <4, 4 to 12, and 12 to 18 years, respectively. Pre- and postintubation attempt mean Spo were 98.9 ± 2.95 and 90.7 ± 1.95%, respectively. Postintubation Spo < 80% were significantly less with one intubation attempt, compared with multiple attempts ( < 0.001). No serious complications were noted. Apneic oxygenation was well tolerated in critically ill children.
该前瞻性病例系列记录了危重症儿科患者在快速顺序插管期间与无呼吸给氧相关的低氧血症和潜在并发症。44例患者分别通过鼻导管以5、10和15 L/分钟的速率接受无呼吸给氧,年龄分别<4岁、4至12岁和12至18岁。插管尝试前和后的平均血氧饱和度分别为98.9±2.95%和90.7±1.95%。与多次尝试相比,单次插管尝试后血氧饱和度<80%的情况明显更少(<0.001)。未观察到严重并发症。危重症儿童对无呼吸给氧耐受性良好。