Wilhelmsburger Krankenhaus Groß-Sand, Hamburg, Germany.
HELIOS Klinikum Emil von Behring, Berlin, Germany.
Cartilage. 2021 Oct;12(4):407-417. doi: 10.1177/1947603519847735. Epub 2019 May 21.
This review presents the current understanding of the etiology, pathogenesis, and how to diagnose and treat osteochondritis dissecans (OCD) at the elbow joint followed by an analysis of particular characteristics and outcomes of the treatment. OCD is seen in patients with open growth plates (juvenile OCD [JOCD] and in adults [AOCD] with closed growth plates [adult OCD). The etiology at smaller joints remains as unclear as for the knee. Mechanical factors (throwing activities [capitulum] seem to play an important role. Clinical symptoms are unspecific. Thus, imaging techniques are most important for the diagnosis. In low-grade and stable lesions, treatment involves rest and different degrees of immobilization until healing. When surgery is necessary, the procedure depends on the OCD stage and on the state of the cartilage. With intact cartilage, retrograde procedures are favorable while with damaged cartilage, several techniques are used. Techniques such as drilling and microfracturing produce a reparative cartilage while other techniques reconstruct the defect with osteochondral grafts or cell-based procedures such as chondrocyte implantation. There is a tendency toward better results when reconstructive procedures for both the bone and cartilage are used. In addition, comorbidities at the joint have to be treated. Severe grades of osteoarthritis are rare.
这篇综述介绍了目前对肘关节剥脱性骨软骨炎(OCD)的病因、发病机制以及诊断和治疗方法的理解,接着分析了其治疗的特殊特征和结果。OCD 可发生在生长板未闭合的成年人(AOCD)和生长板已闭合的青少年(JOCD)中。较小关节的病因与膝关节一样不清楚。机械因素(投掷活动[肱骨小头]似乎起着重要作用。临床症状不具特异性。因此,影像学技术对诊断最为重要。在低度和稳定的病变中,治疗包括休息和不同程度的固定,直到愈合。当需要手术时,手术取决于 OCD 的阶段和软骨的状态。对于软骨完整的病例,逆行手术是有利的,而对于软骨受损的病例,则需要使用多种技术。钻孔和微骨折等技术可产生修复性软骨,而其他技术则使用骨软骨移植物或基于细胞的方法(如软骨细胞植入)来重建缺损。对于同时重建骨和软骨的手术,其结果往往更好。此外,还需要治疗关节的并存疾病。严重程度的骨关节炎较为少见。