Serbian Academy of Sciences and Arts, Heart Failure Center, Faculty of Medicine, Belgrade University Medical Center, Belgrade, Serbia.
Centre for Heart Diseases, University Hospital, Wroclaw, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.
Eur J Heart Fail. 2019 Oct;21(10):1169-1186. doi: 10.1002/ejhf.1531. Epub 2019 Aug 30.
The European Society of Cardiology (ESC) has published a series of guidelines on heart failure (HF) over the last 25 years, most recently in 2016. Given the amount of new information that has become available since then, the Heart Failure Association (HFA) of the ESC recognized the need to review and summarise recent developments in a consensus document. Here we report from the HFA workshop that was held in January 2019 in Frankfurt, Germany. This expert consensus report is neither a guideline update nor a position statement, but rather a summary and consensus view in the form of consensus recommendations. The report describes how these guidance statements are supported by evidence, it makes some practical comments, and it highlights new research areas and how progress might change the clinical management of HF. We have avoided re-interpretation of information already considered in the 2016 ESC/HFA guidelines. Specific new recommendations have been made based on the evidence from major trials published since 2016, including sodium-glucose co-transporter 2 inhibitors in type 2 diabetes mellitus, MitraClip for functional mitral regurgitation, atrial fibrillation ablation in HF, tafamidis in cardiac transthyretin amyloidosis, rivaroxaban in HF, implantable cardioverter-defibrillators in non-ischaemic HF, and telemedicine for HF. In addition, new trial evidence from smaller trials and updated meta-analyses have given us the chance to provide refined recommendations in selected other areas. Further, new trial evidence is due in many of these areas and others over the next 2 years, in time for the planned 2021 ESC guidelines on the diagnosis and treatment of acute and chronic heart failure.
在过去的 25 年里,欧洲心脏病学会 (ESC) 发布了一系列心力衰竭 (HF) 指南,最近一次是在 2016 年。鉴于自那时以来已经有了大量新的信息,ESC 的心力衰竭协会 (HFA) 认识到有必要在一份共识文件中回顾和总结最近的发展。在这里,我们报告了 2019 年 1 月在德国法兰克福举行的 HFA 研讨会的情况。这份专家共识报告既不是指南更新,也不是立场声明,而是一份以共识建议形式总结和达成共识的报告。该报告描述了这些指导声明如何得到证据的支持,提出了一些实际的意见,并强调了新的研究领域以及进展如何改变 HF 的临床管理。我们避免了对 2016 年 ESC/HFA 指南中已经考虑过的信息进行重新解释。根据自 2016 年以来发表的主要试验的证据,我们提出了一些具体的新建议,包括 2 型糖尿病中的钠-葡萄糖共转运蛋白 2 抑制剂、功能性二尖瓣反流的 MitraClip、HF 中的心房颤动消融、心脏转甲状腺素淀粉样变性中的 tafamidis、HF 中的利伐沙班、非缺血性 HF 中的植入式心脏复律除颤器以及 HF 的远程医疗。此外,来自较小试验和更新的荟萃分析的新试验证据使我们有机会在选定的其他领域提供更详细的建议。此外,在未来 2 年内,许多这些领域和其他领域将有新的试验证据公布,届时将为计划于 2021 年发布的 ESC 关于急性和慢性心力衰竭的诊断和治疗指南提供参考。