Child and Adolescent Psychiatry, Solent NHS Trust, Southampton, UK.
Complex Attention and Hyperactivity Disorders Service (CAHDS), Department of Health, Perth, WA, Australia.
Aust N Z J Psychiatry. 2019 Oct;53(10):989-999. doi: 10.1177/0004867419851869. Epub 2019 May 31.
Retrospective recall of dissociative symptoms has been found to mediate the association between childhood abuse and deliberate self-harm (DSH) in later life. To disentangle the effect of recall bias, we tested whether dissociation symptoms ascertained during an acute DSH presentation mediates this link.
All participants with DSH were recruited during emergency presentation. Seventy-one individuals aged 11-17 years with overdose (OD) and/or self-injury (SI) participated in semi-structured interviews and psychiatric assessment to measure abuse and dissociation. An age- and gender-matched comparison group of 42 non-psychiatric patients admitted to the same service were also assessed.
The DSH groups reported significantly higher levels of abuse and dissociation compared to comparison group. Dissociation significantly mediated the association between abuse and DSH. Of the four dissociation subtypes, 'depersonalisation' was the primary mediator. Adolescents with chronic patterns of DSH and the 'OD + SI' self-harm type reported more severe dissociation.
Exposure to abuse significantly increased the risk of DSH in adolescence. This association was mediated by dissociation. Our findings suggest a possible dose-response relationship between dissociation with DSH chronicity and the 'OD + SI' self-harm type, implicating the importance of evaluating dissociation and depersonalisation symptoms as well as abuse exposure in DSH management.
回溯性回忆分离症状被发现可以介导儿童期虐待与日后蓄意自我伤害(DSH)之间的关联。为了厘清回忆偏差的影响,我们测试了在 DSH 急性发作期间确定的分离症状是否会介导这种关联。
所有 DSH 患者均在急诊就诊时招募。71 名年龄在 11-17 岁之间的患者(包括药物过量 [OD] 和/或自我伤害 [SI])参与了半结构化访谈和精神评估,以测量虐待和分离症状。还对同一服务机构中 42 名非精神科患者的年龄和性别相匹配的对照组进行了评估。
DSH 组报告的虐待和分离症状明显高于对照组。分离症状显著介导了虐待和 DSH 之间的关联。在四种分离亚型中,“人格解体”是主要的中介因素。有慢性 DSH 模式和“OD+SI”自我伤害类型的青少年报告了更严重的分离症状。
暴露于虐待显著增加了青少年发生 DSH 的风险。这种关联是通过分离来介导的。我们的研究结果表明,分离与 DSH 的慢性和“OD+SI”自我伤害类型之间可能存在剂量反应关系,这表明在 DSH 管理中评估分离和人格解体症状以及虐待暴露的重要性。