Malloy Kelly A, Draper Erin M, Maglione Ashley K, Seidler Kelly M
Department of Neuro-Ophthalmic Disease, Salus University, Elkins Park, PA, USA.
Eur J Ophthalmol. 2020 Sep;30(5):NP86-NP89. doi: 10.1177/1120672119853133. Epub 2019 Jun 3.
Optic nerve sheath meningiomas and intracavernous arachnoid cysts are both fairly rare conditions, and to the best of our knowledge, have not been previously reported to co-occur in the same patient. Both can cause diplopia, but only ONSMs have been documented to demonstrate progressive worsening of ocular motility.
A 67-year-old woman with blur and diplopia demonstrated a right optic neuropathy and limited ductions bilaterally. Neuroimaging revealed a right optic nerve sheath meningioma and left intracavernous arachnoid cyst. She was conservatively managed with neurosurgical surveillance for 1.5 years, until her diplopia worsened. Ocular motility re-evaluation demonstrated a worsening left abduction deficit, suggesting interval change of the intracavernous cyst, rather than the meningioma.
There are only a few reported cases of cranial nerve VI palsy secondary to a cavernous sinus arachnoid cyst. However, this is the first reported case in a patient with a concurrent optic nerve sheath meningioma, and the first case demonstrating progressive worsening of a sixth cranial nerve palsy from an intracavernous arachnoid cyst. Determining which comorbidity caused worsening of symptoms played a critical role in the management of this patient.
视神经鞘膜瘤和海绵窦内蛛网膜囊肿均为相当罕见的病症,据我们所知,此前尚无同一患者同时出现这两种病症的报道。两者均可导致复视,但仅有视神经鞘膜瘤被记录显示眼球运动逐渐恶化。
一名67岁女性,出现视力模糊和复视,表现为右侧视神经病变及双侧眼球运动受限。神经影像学检查显示右侧视神经鞘膜瘤和左侧海绵窦内蛛网膜囊肿。她接受了1.5年的神经外科监测保守治疗,直至复视加重。眼球运动重新评估显示左侧外展功能障碍加重,提示海绵窦内囊肿而非脑膜瘤出现了间隔期变化。
仅有少数关于海绵窦蛛网膜囊肿继发第六颅神经麻痹的病例报道。然而,这是首例同时患有视神经鞘膜瘤的患者出现该情况的报道,也是首例显示海绵窦内蛛网膜囊肿导致第六颅神经麻痹逐渐加重的病例。确定哪种合并症导致症状加重在该患者的治疗中起到了关键作用。