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脑性瘫痪患儿铜绿假单胞菌导致的化脓性胸膜炎。

Empyema necessitatis due to Pseudomonas aeruginosa in a child with cerebral palsy.

机构信息

Department of Neurology, Hyogo Prefectural Kobe Children's Hospital, Hyogo, Japan.

Department of Neurology, Hyogo Prefectural Kobe Children's Hospital, Hyogo, Japan; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, Japan.

出版信息

J Infect Public Health. 2020 Jan;13(1):140-142. doi: 10.1016/j.jiph.2019.05.013. Epub 2019 Jun 6.

Abstract

Empyema necessitatis (EN) is a rare complication of empyema in which the pleural infection spreads outside the pleural space. Lower airway infections are common among children with cerebral palsy (CP). Although harmless to healthy individuals, Pseudomonas aeruginosa can cause invasive infections, including CP, in immunocompromised hosts. Mycobacterium tuberculosis and Actinomyces spp. have been reported as common causative organisms of EN. However, EN caused by P. aeruginosa has never been reported. We report the case of an 8-year-old girl with CP without tracheotomy who was admitted to our hospital with complaints of fever and increased epileptic seizures. First, she was diagnosed with pneumonia and treated with antibiotics. However, seven days after admission, a palpable mobile mass overlying the lower part of the shoulder blade was noticed. Enhanced magnetic resonance imaging revealed broad high signal area on T2-weighted and diffusion-weighted images, indicating empyema of the left lower lung that had penetrated the pleural wall and spread to the subcutaneous area of the left back. Thus, she was diagnosed with EN. Twelve days after admission, P. aeruginosa was detected from the pus culture. Patients with CP who have chronic lung diseases, such as pneumonia, atelectasis, or empyema, may need careful follow up.

摘要

脓性胸腔积液(empyema necessitatis,EN)是一种罕见的脓性胸腔积液并发症,其中胸膜感染扩散到胸膜腔外。脑瘫(cerebral palsy,CP)患儿常发生下呼吸道感染。铜绿假单胞菌对健康个体无害,但可在免疫功能低下的宿主中引起侵袭性感染,包括 CP。分枝杆菌和放线菌被报道为脓性胸腔积液的常见病原体。然而,由铜绿假单胞菌引起的脓性胸腔积液从未有过报道。我们报告了一例 8 岁女孩,患有 CP 但未行气管切开术,因发热和癫痫发作增加而入住我院。首先,她被诊断为肺炎并接受了抗生素治疗。然而,入院后 7 天,发现肩胛下部有一个可触及的移动肿块。增强磁共振成像显示 T2 加权和弥散加权图像上广泛的高信号区,表明左侧下肺的脓性胸腔积液已穿透胸膜壁并扩散到左侧背部的皮下区域。因此,她被诊断为脓性胸腔积液。入院后 12 天,从脓液培养中检出铜绿假单胞菌。患有慢性肺部疾病(如肺炎、肺不张或脓性胸腔积液)的 CP 患者可能需要密切随访。

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