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骨质疏松性骨折的二级预防:2016 年 1 月至 2018 年 1 月期间里尔大学医院骨折联络服务的评估。

Secondary prevention of osteoporotic fractures: evaluation of the Lille University Hospital's Fracture Liaison Service between January 2016 and January 2018.

机构信息

Department of Rheumatology, Lille University Hospital, Lille, France.

Department of Gerontology, Lille University Hospital, Lille, France.

出版信息

Osteoporos Int. 2019 Sep;30(9):1779-1788. doi: 10.1007/s00198-019-05036-0. Epub 2019 Jun 5.

Abstract

UNLABELLED

The purpose of this study was to assess the performance of our Fracture Liaison Service (FLS) over a period of 2 years. Osteoporosis medication was prescribed for 243 patients, and zoledronic acid was the main drug prescribed (60.2%).

INTRODUCTION

A Fracture Liaison Service (FLS) was implemented at Lille University Hospital in 2016. The main purpose of this study was to assess the performance of the FLS using criteria proposed by the International Osteoporosis Foundation (IOF).

METHODS

The criteria used were patient identification, patient evaluation, post-fracture assessment timing, vertebral-fracture identification, blood and bone mineral density (BMD) testing, falls prevention, multifaceted health and lifestyle risk-factor assessment, and medication initiation and review.

RESULTS

Between January 2016 and January 2018, 736 patients (≥ 50 years old) with a recent history of fragility fracture (≤ 12 months) were identified. The identification rate for hip fractures was 74.2%. However, patient evaluation for all type of fractures was quite low (30.3%) since many patients failed to attend the FLS unit. The reasons for non-attendance were refusal, agreed but subsequently failed to attend, and still waiting to be seen. In all, 256 patients (76.6% female, mean (SD) age 74.3 (11.0) years) were seen at the FLS. Mean (SD) post-fracture assessment timing was 13.3 (9.3) weeks. Of the 139 patients seen for a non-vertebral fracture, 103 were assessed for vertebral fractures, and at least one new vertebral fracture was found in 45 of them (43.7%). Osteoporosis medication was prescribed for 243 (94.9%) patients. The main osteoporosis drug prescribed was zoledronic acid (60.2%).

CONCLUSIONS

Secondary prevention of osteoporotic fractures has improved since the implementation of the FLS. However, patient identification, patient evaluation, and post-fracture assessment timing still need to be improved.

摘要

目的

本研究旨在评估我们的骨折联络服务(FLS)在 2 年期间的表现。为 243 名患者开具了骨质疏松症药物,其中主要开具的药物为唑来膦酸(60.2%)。

引言

2016 年,里尔大学医院实施了骨折联络服务(FLS)。本研究的主要目的是使用国际骨质疏松基金会(IOF)提出的标准来评估 FLS 的表现。

方法

使用的标准包括患者识别、患者评估、骨折后评估时间、椎体骨折识别、血液和骨密度(BMD)检测、预防跌倒、多方面的健康和生活方式风险因素评估以及药物的启动和审查。

结果

2016 年 1 月至 2018 年 1 月期间,共识别出 736 名(≥50 岁)有近期脆性骨折(≤12 个月)病史的患者。髋部骨折的识别率为 74.2%。然而,所有类型骨折的患者评估率都相当低(30.3%),因为许多患者未能到 FLS 就诊。未就诊的原因包括拒绝、同意但随后未能就诊以及仍在等待就诊。共有 256 名(76.6%为女性,平均年龄(SD)74.3(11.0)岁)患者到 FLS 就诊。骨折后评估的平均(SD)时间为 13.3(9.3)周。在 139 名因非椎体骨折就诊的患者中,有 103 名患者接受了椎体骨折评估,其中 45 名(43.7%)患者至少发现了一处新的椎体骨折。为 243 名(94.9%)患者开具了骨质疏松症药物。主要开具的骨质疏松症药物为唑来膦酸(60.2%)。

结论

自 FLS 实施以来,骨质疏松性骨折的二级预防有所改善。然而,患者识别、患者评估和骨折后评估时间仍需改进。

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