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世界卫生组织烟草控制框架公约对全球卷烟消费的影响:使用中断时间序列分析和样本内预测事件建模的准实验评估。

Impact of the WHO Framework Convention on Tobacco Control on global cigarette consumption: quasi-experimental evaluations using interrupted time series analysis and in-sample forecast event modelling.

机构信息

Global Strategy Lab, Dahdaleh Institute for Global Health Research, Faculty of Health and Osgoode Hall Law School, York University, 4700 Keele Street, Dahdaleh Building 2120, Toronto, Ontario, M3J 1P3 Canada

Department of Global Health and Population, Harvard T H Chan School of Public Health, Harvard University, Boston, MA, USA.

出版信息

BMJ. 2019 Jun 19;365:l2287. doi: 10.1136/bmj.l2287.

Abstract

OBJECTIVE

To evaluate the impact of the WHO Framework Convention on Tobacco Control (FCTC) on global cigarette consumption.

DESIGN

Two quasi-experimental impact evaluations, using interrupted time series analysis (ITS) and in-sample forecast event modelling.

SETTING AND POPULATION

71 countries for which verified national estimates of cigarette consumption from 1970 to 2015 were available, representing over 95% of the world's cigarette consumption and 85% of the world's population.

MAIN OUTCOME MEASURES

The FCTC is an international treaty adopted in 2003 that aims to reduce harmful tobacco consumption and is legally binding on the 181 countries that have ratified it. Main outcomes were annual national estimates of cigarette consumption per adult from 71 countries since 1970, allowing global, regional, and country comparisons of consumption levels and trends before and after 2003, with counterfactual control groups modelled using pre-intervention linear time trends (for ITS) and in-sample forecasts (for event modelling).

RESULTS

No significant change was found in the rate at which global cigarette consumption had been decreasing after the FCTC's adoption in 2003, using either ITS or event modelling. Results were robust after realigning data to the year FCTC negotiations commenced (1999), or to the year when the FCTC first became legally binding in each country. By contrast to global consumption, high income and European countries showed a decrease in annual consumption by over 1000 cigarettes per adult after 2003, whereas low and middle income and Asian countries showed an increased annual consumption by over 500 cigarettes per adult when compared with a counterfactual event model.

CONCLUSIONS

This study finds no evidence to indicate that global progress in reducing cigarette consumption has been accelerated by the FCTC treaty mechanism. This null finding, combined with regional differences, should caution against complacency in the global tobacco control community, motivate greater implementation of proven tobacco control policies, encourage assertive responses to tobacco industry activities, and inform the design of more effective health treaties.

摘要

目的

评估世界卫生组织烟草控制框架公约(FCTC)对全球卷烟消费的影响。

设计

两项准实验性影响评估,使用中断时间序列分析(ITS)和样本内预测事件建模。

设置和人群

71 个国家提供了 1970 年至 2015 年经核实的卷烟消费国家估计数,占全球卷烟消费的 95%以上,占世界人口的 85%。

主要观察指标

FCTC 是 2003 年通过的一项国际条约,旨在减少有害烟草消费,对 181 个批准该条约的国家具有法律约束力。主要结果是自 1970 年以来 71 个国家的成人每年卷烟消费的国家估计数,允许在 2003 年之前和之后对消费水平和趋势进行全球、区域和国家间比较,使用干预前线性时间趋势(ITS)和样本内预测(事件建模)建模对照控制组。

结果

在 FCTC 于 2003 年通过后,全球卷烟消费下降的速度没有发现显著变化,无论是使用 ITS 还是事件建模。在将数据与 FCTC 谈判开始的年份(1999 年)或每个国家首次具有法律约束力的年份对齐后,结果仍然稳健。与全球消费情况相反,高收入和欧洲国家在 2003 年后每个成人每年的消费量减少了 1000 多支香烟,而低收入和中等收入以及亚洲国家的消费量每年增加了 500 多支香烟与反事实事件模型相比。

结论

本研究没有发现任何证据表明 FCTC 条约机制加速了全球减少卷烟消费的进展。这一零发现,加上区域差异,应该告诫全球烟草控制界不要自满,激励更有效地实施经过验证的烟草控制政策,鼓励对烟草业活动采取果断回应,并为更有效的卫生条约设计提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a6c/6582266/ecfb8d2dea43/hofs048712.f1.jpg

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