肾上腺原发性小细胞神经内分泌癌
Primary small cell neuroendocrine carcinoma of adrenal gland.
作者信息
Ogawa Kosuke, Shimizu Yousuke, Uketa Shoko, Utsunomiya Noriaki, Kida Kazutaka, Ishihara Misa, Hashimoto Kimio, Kanamaru Sojun
机构信息
1Department of Urology, Kobe City Nishi-Kobe Medical Center, 7-1 Kojidai, 5-chome Nishiku, Kobe, Hyogo 651-2273 Japan.
2Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
出版信息
Int Cancer Conf J. 2019 Mar 27;8(3):122-125. doi: 10.1007/s13691-019-00368-4. eCollection 2019 Jul.
Neuroendocrine tumors are an extremely rare form of retroperitoneum tumor. A 79-year-old man presented with abdominal pain. Computed tomography and magnetic resonance imaging revealed a 51 × 36 mm mass in the left adrenal gland. Gastrofiberscopy, colonfiberscopy and positron emission tomography were performed and showed no lesions or other malignancies. Endocrine tests were normal. Two months later, the mass had grown to 68 × 52 mm. Suspecting a malignant tumor, we performed laparoscopic adrenalectomy. Histopathological diagnosis revealed the tumor was small cell neuroendocrine carcinoma. No other malignancies were revealed, so we diagnosed primary small cell neuroendocrine carcinoma of adrenal gland. To our knowledge, this is only the third report in English of primary small cell neuroendocrine carcinoma of the adrenal gland and the first report that is confined to the adrenal gland. Adrenal masses are often misdiagnosed as adenoma; however, we need to raise awareness of the potential for malignant adrenal tumors such as the rarer small cell neuroendocrine carcinoma.
神经内分泌肿瘤是一种极为罕见的腹膜后肿瘤。一名79岁男性因腹痛就诊。计算机断层扫描和磁共振成像显示左肾上腺有一个51×36毫米的肿块。进行了胃镜、结肠镜检查和正电子发射断层扫描，未发现病变或其他恶性肿瘤。内分泌检查正常。两个月后，肿块增大至68×52毫米。怀疑为恶性肿瘤，我们进行了腹腔镜肾上腺切除术。组织病理学诊断显示该肿瘤为小细胞神经内分泌癌。未发现其他恶性肿瘤，因此我们诊断为肾上腺原发性小细胞神经内分泌癌。据我们所知，这是英文文献中关于肾上腺原发性小细胞神经内分泌癌的第三例报告，也是首例局限于肾上腺的报告。肾上腺肿块常被误诊为腺瘤；然而，我们需要提高对罕见的小细胞神经内分泌癌等恶性肾上腺肿瘤可能性的认识。
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