Kumpe D A, Rao C V, Garcia J H, Heck A F
J Comput Assist Tomogr. 1979 Jun;3(3):324-30. doi: 10.1097/00004728-197906000-00004.
Neuroradiological findings in two cases of histologically confirmed intracranial sarcoidosis are presented, one with periaqueductal granulomata causing aqueduct obstruction. The granulomatous aggregation was of slightly greater attenuation than normal brain parenchyma and did enhance homogeneously following contrast medium administration. No direct signs of basal arachnoiditis could be found on computed tomography (CT) in the other case in which hydrocephalus was produced by a granulomatous infiltration of the fourth ventricle and cisterna magna. The neuropathological and pertinent clinical and laboratory manifestations of neurosarcoidosis are reviewed as a means of predicting recognizable CT patterns of the entity.
本文报告了两例经组织学证实的颅内结节病的神经放射学表现,其中一例有导水管周围肉芽肿导致导水管梗阻。肉芽肿聚集区的密度略高于正常脑实质,注射造影剂后呈均匀强化。另一例因第四脑室和小脑延髓池的肉芽肿浸润导致脑积水,计算机断层扫描(CT)未发现基底蛛网膜下腔炎的直接征象。本文回顾了神经结节病的神经病理学及相关临床和实验室表现,作为预测该疾病可识别CT表现的一种方法。