Prattley Sarah, New Francesca, Davies Melissa
Salisbury District Hospital, Odstock Road, Salisbury, SP28BJ UK.
Spinal Cord Ser Cases. 2019 Apr 15;5:34. doi: 10.1038/s41394-019-0177-9. eCollection 2019.
Spinal cord injury (SCI) patients are at increased risk of bladder cancer. A rare variation of this is a malignancy arising or including the suprapubic catheter (SPC) tract.
We present the first case series of malignancy of the SPC tract in SCI patients, including a case of mucinous adenocarcinoma, squamous cell carcinoma and sarcoma. Presentation of patients ranged from bleeding at the site of the SPC to a rapidly growing mass. All three patients were thoroughly investigated, and management was bespoke to the extent of disease and their physiological state at the time of diagnosis. This ranged from extensive surgical intervention including cystectomy, partial sigmoidectomy, excision of the abdominal wall with reconstruction and ileal conduit formation to palliation.
SCI patients represent 50% of all known published cases of malignancy of the SPC tract. Presentation and diagnosis can be challenging; however, prompt investigation and intervention are essential given the high degree of morbidity and mortality. Routine check of the SPC site may be indicated in those patients in whom the SPC has been present for more than 5 years.
脊髓损伤(SCI)患者患膀胱癌的风险增加。其中一种罕见的情况是在耻骨上导管(SPC)通道处发生或包含的恶性肿瘤。
我们展示了首例脊髓损伤患者耻骨上导管通道恶性肿瘤的病例系列,包括一例黏液腺癌、鳞状细胞癌和肉瘤。患者的表现从耻骨上导管部位出血到迅速生长的肿块不等。对所有三名患者都进行了全面检查,并根据疾病程度和诊断时的生理状态进行了定制化治疗。治疗范围从包括膀胱切除术、部分乙状结肠切除术、腹壁切除并重建以及回肠造口术的广泛手术干预到姑息治疗。
脊髓损伤患者占所有已知耻骨上导管通道恶性肿瘤已发表病例的50%。临床表现和诊断可能具有挑战性;然而,鉴于其高度的发病率和死亡率,及时的检查和干预至关重要。对于耻骨上导管留置超过5年的患者,可能需要对导管部位进行常规检查。