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右美托咪定在一例重度癌痛患者中的应用

Dexmedetomidine Use in a Case of Severe Cancer Pain.

作者信息

Seymore Russell Jeffrey, Manis Melanie M, Coyne Patrick J

出版信息

J Pain Palliat Care Pharmacother. 2019 Mar-Jun;33(1-2):34-41. doi: 10.1080/15360288.2019.1629520. Epub 2019 Jun 26.

Abstract

A 58-year-old male with chronic pancreatitis was seen by the palliative care service for pain and agitation related to a recent diagnosis of disseminated abdominal cancer. Increasing symptom burden, including pain and nausea, in the face of escalating doses of multiple opioid and sedative medications resulted in the addition of dexmedetomidine to successfully control his symptoms. Visceral sensitization related to his chronic pancreatitis likely increased his pain perception and required a multimodal approach to control his symptoms.

摘要

一名58岁的慢性胰腺炎男性患者因近期诊断为播散性腹部癌而出现疼痛和烦躁不安,接受了姑息治疗服务。面对多种阿片类药物和镇静药物剂量不断增加,症状负担却日益加重,包括疼痛和恶心,于是加用右美托咪定成功控制了他的症状。与他的慢性胰腺炎相关的内脏致敏可能增加了他的疼痛感知,需要采用多模式方法来控制他的症状。

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