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第六届世界肺动脉高压研讨会:旧貌换新颜。

The 6th World Symposium on Pulmonary Hypertension: what's old is new.

作者信息

Condon David F, Nickel Nils P, Anderson Ryan, Mirza Shireen, de Jesus Perez Vinicio A

机构信息

Division of Pulmonary and Critical Care Medicine, Stanford University, Stanford, USA.

Vera Moulton Wall Center for Pulmonary Vascular Research, Stanford University, Stanford, USA.

出版信息

F1000Res. 2019 Jun 19;8. doi: 10.12688/f1000research.18811.1. eCollection 2019.

Abstract

In February 2018, the 6th World Symposium on Pulmonary Hypertension (WSPH) brought together experts from various disciplines to review the most relevant clinical and scientific advances in the field of PH over the last 5 years. Based on careful review and discussions by members of the different task forces, major revisions were made on the hemodynamic definition for various forms of PH and new genes were added to the list of genetic markers associated with pulmonary arterial hypertension (PAH) and pulmonary veno-occlusive disease. In addition, the use of risk stratification tools was encouraged as a strategy to reduce one-year mortality risk in PAH patients through early implementation of PAH therapies. While members of the medical community are still debating some of the proposed changes, the new WSPH guidelines advocate early diagnosis and initiation of combination therapy to reduce mortality and improve quality of life in patients with PH.

摘要

2018年2月,第六届世界肺动脉高压研讨会(WSPH)汇聚了各学科专家,以回顾过去5年肺动脉高压领域最相关的临床和科学进展。基于不同工作组成员的仔细审查和讨论,对各种形式肺动脉高压的血流动力学定义进行了重大修订,并在与肺动脉高压(PAH)和肺静脉闭塞性疾病相关的遗传标记列表中增加了新基因。此外,鼓励使用风险分层工具,作为通过早期实施PAH治疗来降低PAH患者一年死亡风险的策略。虽然医学界成员仍在就一些提议的更改进行辩论,但新的WSPH指南提倡早期诊断并开始联合治疗,以降低PH患者的死亡率并改善其生活质量。

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