肥胖症患者体重指数（BMI）≥50kg/m2 行单吻合口胃旁路术与 Roux-en-Y 胃旁路术和袖状胃切除术的对比：系统评价
One Anastomosis Gastric Bypass in Morbidly Obese Patients with BMI ≥ 50 kg/m: a Systematic Review Comparing It with Roux-En-Y Gastric Bypass and Sleeve Gastrectomy.
机构信息
Whittington Hospital, London, N19 5NF, UK.
Mexican Institute of Social Security, Mexico City, Mexico.
出版信息
Obes Surg. 2019 Sep;29(9):3039-3046. doi: 10.1007/s11695-019-04034-9.
BACKGROUND
To explore the role of one anastomosis (Mini) gastric bypass (OAGB) for the super-obese patients.
METHOD
Literature review was performed in March 2019 as per PRISMA guidelines.
RESULTS
A total of 318 patients were identified. Mean age was 31.8 years. Mean body mass index (BMI) was 57.4 kg/m. The mean operative time was 93.1 min with median length of stay of 4.5 days. The biliopancreatic limb (BPL) varied from 190 to 350 cm(median 280 cm). Early mortality was 0.31% with seven complications (including 1 revisional surgery). Leak rate was 0%. Mean %excess weight loss (EWL) at 12, 18-24 and 60 months was 67.7%, 71.6% and 90.75%, respectively.
CONCLUSIONS
OAGB is a safe and effective option for management of super and super-super obese patients with tailoring of the BPL. Larger comparison, follow-up and randomised trials are necessary to validate these findings.
背景
探讨单吻合口（迷你）胃旁路术（OAGB）治疗超肥胖患者的作用。
方法
根据 PRISMA 指南，于 2019 年 3 月进行文献回顾。
结果
共纳入 318 例患者。平均年龄为 31.8 岁。平均体重指数（BMI）为 57.4kg/m²。平均手术时间为 93.1 分钟，中位住院时间为 4.5 天。胆胰支（BPL）长度为 190-350cm（中位数 280cm）。早期死亡率为 0.31%，发生 7 例并发症（包括 1 例再次手术）。漏诊率为 0%。术后 12、18-24、60 个月的体质量减轻百分比（EWL）分别为 67.7%、71.6%和 90.75%。
结论
OAGB 是治疗超肥胖和超超级肥胖患者的安全有效的方法，可通过调整胆胰支的长度来实现。需要更大规模的比较、随访和随机试验来验证这些发现。
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