Department of Neurology, Northwestern University Feinberg School of Medicine, 710 North Lake Shore Drive, Abbott Hall 524, Chicago, IL 60611, USA.
Department of Neurology, Northwestern University Feinberg School of Medicine, 710 North Lake Shore Drive, Abbott Hall 521, Chicago, IL 60611, USA.
Neurol Clin. 2019 Aug;37(3):601-613. doi: 10.1016/j.ncl.2019.04.004.
Circadian rhythms are present in nearly all organisms studied, and are present throughout the human body. The proper coordination of these rhythms, both within the body, and with respect to the environment appears to be important for overall health. This article reviews the available data looking at the association between circadian dysregulation and cardiometabolic, neurologic, and neurodegenerative disease risk. In addition we discuss the limited but growing evidence supporting the use of circadian-based interventions to improve overall health.
昼夜节律存在于几乎所有被研究的生物中,并且存在于人体的各个部位。这些节律的正确协调,无论是在体内还是与环境之间,似乎对整体健康都很重要。本文综述了现有数据,探讨了昼夜节律失调与心血管代谢、神经和神经退行性疾病风险之间的关联。此外,我们还讨论了支持使用基于昼夜节律的干预措施来改善整体健康的有限但不断增加的证据。