Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, UK.
Clin Exp Optom. 2020 Jan;103(1):31-43. doi: 10.1111/cxo.12937. Epub 2019 Jul 1.
Technological advancements in the design of soft and scleral contact lenses have led to the development of customised, aberration-controlling corrections for patients with keratoconus. As the number of contact lens manufacturers producing wavefront-guided corrections continues to expand, clinical interest in this customisable technology is also increasing among both patients and practitioners. This review outlines key issues surrounding the measurement of ocular aberrations for patients with keratoconus, with a particular focus on the possible factors affecting the repeatability of Hartmann-Shack aberrometry measurements. This review also discusses and compares the relative successes of studies investigating the design and fitting of soft and scleral customised contact lenses for patients with keratoconus. A series of key limitations that should be considered before designing customised contact lens corrections is also described. Despite the challenges of producing and fitting customised lenses, improvements in visual performance and comfortable wearing times, as provided by these lenses, could help to reduce the rate of keratoplasty in keratoconic patients, thereby significantly reducing clinical issues related to corneal graft surgery. Furthermore, enhancements in optical correction, provided by customised lenses, could lead to increased independence, particularly among young adult keratoconic patients, therefore leading to improvements in quality of life.
软性巩膜接触镜设计方面的技术进步,使得能够为圆锥角膜患者开发定制、像差控制的矫正方法。随着越来越多的隐形眼镜制造商生产波前引导矫正方法,患者和医生对这种定制技术的兴趣也在不断增加。本综述概述了圆锥角膜患者眼像差测量方面的一些关键问题,特别关注可能影响哈特曼-夏克(Hartmann-Shack)像差仪测量重复性的因素。本综述还讨论和比较了针对圆锥角膜患者设计和适配软性和巩膜定制接触镜的研究的相对成功。本文还描述了在设计定制接触镜矫正方法之前需要考虑的一系列关键限制因素。尽管定制镜片的生产和适配存在挑战,但这些镜片在提高视觉性能和佩戴舒适度方面的改进,有助于降低圆锥角膜患者的角膜移植率,从而显著减少与角膜移植手术相关的临床问题。此外,定制镜片提供的光学矫正增强,可能会带来更高的独立性,特别是对于年轻的成年圆锥角膜患者,从而提高生活质量。