Department of Public Health, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, Basel 4002, Switzerland; University of Basel, Basel 4003, Switzerland.
Rotterdam Centre for Tropical Medicine, Bovenstraat 21, 3077 BB Rotterdam, The Netherlands.
Trends Parasitol. 2019 Aug;35(8):590-592. doi: 10.1016/j.pt.2019.06.007. Epub 2019 Jun 29.
Post-kala-azar dermal leishmaniasis (PKDL) is a parasitic skin infection which can occur after visceral leishmaniasis (VL). Recent xenodiagnosis studies (Mondal et al., Clin. Infect. Dis., 2018) have uncovered the infectiousness of PKDL. When including this in a transmission model, PKDL cases appear as an important reservoir of infection, likely frustrating the VL elimination efforts on the Indian subcontinent.
内脏利什曼病(VL)治愈后可能会发生皮肤利什曼病(PKDL),这是一种寄生虫引起的皮肤感染。最近的体外诊断研究(Mondal 等人,临床传染病,2018)揭示了 PKDL 的传染性。如果将其纳入传播模型,PKDL 病例将成为感染的重要传染源,可能会破坏印度次大陆消除 VL 的努力。