Division of Nephrology and.
Department of Medicine, University of California, San Francisco, California.
Clin J Am Soc Nephrol. 2019 Aug 7;14(8):1142-1150. doi: 10.2215/CJN.00060119. Epub 2019 Jul 11.
Improving the quality of CKD care has important public health implications to delay disease progression and prevent ESKD. National trends of the quality of CKD care are not well established. Furthermore, it is unknown whether gaps in quality of care are due to lack of physician awareness of CKD status of patients or other factors.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a national, serial, cross-sectional study of visits to office-based ambulatory care practices for adults with diagnosed CKD from the years 2006 to 2014. We assessed the following quality indicators: () BP measurement, () uncontrolled hypertension, () uncontrolled diabetes, () angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use among patients with hypertension, () statin use if age ≥50 years old, and (6) nonsteroidal anti-inflammatory drug use. Using multivariable linear regression and chi-squared analysis, we examined the change in quality performance over time.
Between 2006 and 2014, there were 7099 unweighted visits for patients with CKD representing 186,961,565 weighted visits. There was no difference in the prevalence of uncontrolled hypertension (>130/80 mm Hg) over time (46% in 2006-2008 versus 48% in 2012-2014; =0.50). There was a high prevalence of uncontrolled diabetes in 2012-2014 (40% for hemoglobin A1c >7%). The prevalence of ACEi/ARB use decreased from 45% in 2006-2008 to 36% in 2012-2014, which did not reach statistical significance (=0.07). Statin use in patients with CKD who were 50 years or older was low and remained unchanged from 29% in 2006-2008 to 31% in 2012-2014 (=0.92).
In a nationally representative dataset, we found that patients with CKD had a high prevalence of uncontrolled hypertension and diabetes and a low use of statins that did not improve over time and was not concordant with guidelines.
提高慢性肾脏病(CKD)护理质量对延缓疾病进展和预防终末期肾病(ESKD)具有重要的公共卫生意义。目前尚不清楚全国范围内 CKD 护理质量的趋势,也不知道护理质量的差距是由于医生对患者 CKD 状况的认识不足还是其他因素造成的。
方法、设置、参与者和测量:我们对 2006 年至 2014 年期间在办公室就诊的成年 CKD 患者进行了一项全国性的、连续的、横断面研究。我们评估了以下质量指标:(1)血压测量,(2)未控制的高血压,(3)未控制的糖尿病,(4)高血压患者中血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂的使用,(5)年龄≥50 岁时他汀类药物的使用,以及(6)非甾体抗炎药的使用。我们使用多变量线性回归和卡方分析来检查随着时间的推移质量表现的变化。
在 2006 年至 2014 年间,有 7099 次未加权的 CKD 患者就诊,代表了 186961565 次加权就诊。未控制的高血压(>130/80mmHg)的患病率在这段时间内没有变化(2006-2008 年为 46%,2012-2014 年为 48%;=0.50)。2012-2014 年,未控制的糖尿病患病率较高(血红蛋白 A1c>7%的患者为 40%)。ACEi/ARB 的使用比例从 2006-2008 年的 45%降至 2012-2014 年的 36%,但差异无统计学意义(=0.07)。在年龄≥50 岁的 CKD 患者中,他汀类药物的使用比例较低,且从 2006-2008 年的 29%到 2012-2014 年的 31%没有变化(=0.92)。
在一个具有全国代表性的数据集里,我们发现 CKD 患者的高血压和糖尿病未控制的比例较高,他汀类药物的使用率较低,而且这些情况并没有随着时间的推移而改善,也与指南不一致。