Detrait Marie, de Berranger Eva, Dulery Remy, Ménard Anne-Lise, Thépot Sylvain, Toprak Selami Kocak, Turlure Pascal, Yakoub-Agha Ibrahim, Guillaume Thierry
CHU de Nancy, hôpitaux de Brabois, service d'hématologie, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.
CHRU de Lille, hôpital Jeanne-de-Flandres, service d'hématologie pédiatrique, avenue Eugène-Aviné, 59037 Lille cedex, France.
Bull Cancer. 2020 Jan;107(1S):S28-S35. doi: 10.1016/j.bulcan.2019.05.002. Epub 2019 Jul 11.
Acute and chronic renal failures are very common after allogeneic HSCT. These complications have a real impact on mortality and morbidity of transplant recipients. Within the framework of the ninth workshops of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held in Lille in September 2018, various causes and mechanisms of renal failure, diagnostic work-up, treatment and recommendations to limit renal failure after transplantation are reviewed. Recommendations to adjust medications to avoid renal failure are also proposed in this article.
急性和慢性肾衰竭在异基因造血干细胞移植后非常常见。这些并发症对移植受者的死亡率和发病率有实际影响。在2018年9月于里尔举行的法语国家骨髓移植和细胞治疗协会(SFGM-TC)第九次实践协调研讨会上,对肾衰竭的各种病因和机制、诊断检查、治疗以及限制移植后肾衰竭的建议进行了回顾。本文还提出了调整药物以避免肾衰竭的建议。