坏死性黄色肉芽肿作为冒烟型骨髓瘤的首发表现
Necrobiotic Xanthogranuloma as the Presenting Manifestation of Smouldering Myeloma.
作者信息
Makkar Nayani, Niyas Vettakkara Kandy Muhammed, Swain Satish, Sethi Prayas, Nischal Neeraj, Agarwal Shipra, Ramam M, Wig Naveet
机构信息
Department of Medicine, All India Institute of Medical Sciences, New Delhi.
Department of Pathology, All India Institute of Medical Sciences, New Delhi.
出版信息
J Assoc Physicians India. 2019 Mar;67(3):87-88.
Necrobiotic xanthogranuloma is a rare dermatological manifestation of underlying hematological malignancies, in particular, when associated with paraproteinemia. These patients who are clinically symptomatic with chronic papules, nodules or plaques which demonstrate a histopathological pattern suggestive of extensive and frequently confluent areas of necrobiosis with granulomatous infiltration, warrant evaluation for an underlying monoclonal gammopathy.
坏死性黄色肉芽肿是潜在血液系统恶性肿瘤罕见的皮肤表现，尤其是与副蛋白血症相关时。这些患者临床上有慢性丘疹、结节或斑块的症状，其组织病理学模式提示存在广泛且常融合的坏死区域并伴有肉芽肿浸润，需要评估是否存在潜在的单克隆丙种球蛋白病。
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