Centro Hospitalar Universitário de Lisboa Norte, Psychiatry Department, Lisbon, Portugal; Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Clarkson University, Potsdam, NY, USA.
Schizophr Res. 2019 Sep;211:69-78. doi: 10.1016/j.schres.2019.07.001. Epub 2019 Jul 12.
A disturbance of "minimal self," - of the immediate sense of mine-ness inherent in experience-is hypothesized to be the core disturbance in schizophrenia. Research with the Examination of Anomalous Self Experience (EASE) has demonstrated the selective aggregation of anomalous self-experiences in the schizophrenia spectrum. Conceptual research suggests that anomalous world experiences, including changes in the experience of space, time, and other persons, occur alongside anomalous self-experiences and are an important aspect of subjectivity in schizophrenia. The Examination of Anomalous World Experience (EAWE) is a recently published interview format designed to explore changes in world experience in schizophrenia. In the current study, 24 hospital outpatients with non-affective first-episode psychosis and 24 healthy-control participants were assessed with the EAWE and the EASE. First episode psychosis patients had total EAWE and EASE scores that were both, on average, significantly higher than the healthy-control group. EAWE and EASE scores were highly correlated, even after removing overlapping items. The distribution of EAWE items and subtypes in the first-episode psychosis sample was heterogeneous. We conclude that anomalous world experiences represent a relevant aspect of first-episode psychosis, and that they may be related to the self-disturbances thought to underlie schizophrenia spectrum disorders.
自我“最小意识”的紊乱,即经验中固有的自我意识的即刻感觉紊乱,被假设为精神分裂症的核心紊乱。使用异常自我体验检查(EASE)的研究表明,异常自我体验在精神分裂症谱系中呈选择性聚集。概念研究表明,异常的世界体验,包括空间、时间和其他人的体验的变化,与异常的自我体验同时发生,是精神分裂症主观性的一个重要方面。异常世界体验检查(EAWE)是一种最近发表的访谈格式,旨在探索精神分裂症中世界体验的变化。在当前的研究中,24 名非情感首发精神病住院患者和 24 名健康对照组参与者接受了 EAWE 和 EASE 的评估。首发精神病患者的 EAWE 和 EASE 总分均显著高于健康对照组。即使在去除重叠项目后,EAWE 和 EASE 评分也高度相关。首发精神病样本中 EAWE 项目和亚型的分布具有异质性。我们得出结论,异常的世界体验代表了首发精神病的一个相关方面,它们可能与被认为是精神分裂症谱系障碍基础的自我紊乱有关。