Interdisciplinary Center for Innovation in Biotechnology and Neuroscience, Department of Anatomy, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Department of Neurology, Lanka Hospital, Colombo, Sri Lanka.
Dement Geriatr Cogn Disord. 2019;47(4-6):198-208. doi: 10.1159/000497743. Epub 2019 Jul 16.
Sri Lanka is a rapidly aging country, where dementia prevalence will increase significantly in the future. Thus, inexpensive and sensitive cognitive screening tools are crucial.
To assess the reliability, validity, and diagnostic accuracy of the Sinhalese version of the Addenbrooke's Cognitive Examination-Revised (ACE-R s).
The ACE-R was translated into Sinhala with cultural and linguistic adaptations and administered, together with the Sinhala version of the Montreal Cognitive Assessment (MoCA), to 99 patients with dementia and 93 gender-matched controls.
The ACE-R s cutoff score for dementia was 80 (sensitivity 91.9%, specificity 76.3%). The areas under the curve for the ACE-R s, Mini-Mental State Examination (MMSE) and MoCA were 0.90, 0.86, and 0.86, respectively. The -ACE-R s had good interrater reliability (intraclass correlation = 0.94), test-retest reliability (intraclass correlation = 0.99), and internal consistency (Cronbach's α = 0.8442).
The ACE-R s is sensitive, specific and reliable to detect dementia in persons aged ≥50 years in a Sinhala-speaking population and its diagnostic accuracy is superior to previously validated tools (MMSE and MoCA).
斯里兰卡是一个人口迅速老龄化的国家,未来痴呆症的患病率将显著增加。因此,需要使用廉价且敏感的认知筛查工具。
评估阿登布鲁克认知测验修订版(ACE-R s)的僧伽罗语版本的信度、效度和诊断准确性。
ACE-R 被翻译成僧伽罗语,并进行了文化和语言适应性调整,然后与蒙特利尔认知评估(MoCA)的僧伽罗语版本一起,对 99 名痴呆症患者和 93 名性别匹配的对照组进行了评估。
ACE-R s 的痴呆症截断值为 80(敏感性 91.9%,特异性 76.3%)。ACE-R s、简易精神状态检查(MMSE)和 MoCA 的曲线下面积分别为 0.90、0.86 和 0.86。ACE-R s 的组内相关系数为 0.94,重测信度为 0.99,内部一致性为 0.8442(Cronbach's α)。
ACE-R s 对≥50 岁的僧伽罗语人群中痴呆症的检测具有敏感性、特异性和可靠性,其诊断准确性优于之前验证的工具(MMSE 和 MoCA)。