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在基层医疗服务使用者中使用脂质蓄积产物指数进行心血管风险评估:一项横断面研究。

Cardiovascular risk assessment using the lipid accumulation product index among primary healthcare users: a cross-sectional study.

作者信息

Vieira Jallyne Nunes, Braz Marina Augusta Dias, Gomes Flayane Oliveira, Silva Priscilla Rafaella da, Santos Ohanna Thays de Medeiros, Rocha Ilanna Marques Gomes da, Sousa Iasmin Matias de, Fayh Ana Paula Trussardi

机构信息

Undergraduate Student at Health Science College of Trairi, Universidade Federal do Rio Grande do Norte (UFRN), Santa Cruz (RN), Brazil.

Undergraduate Student at Health Science College of Trairi, Universidade Federal do Rio Grande do Norte (UFRN), Santa Cruz, RN, Brazil.

出版信息

Sao Paulo Med J. 2019 Jul 15;137(2):126-131. doi: 10.1590/1516-3180.2018.0293240119.

Abstract

BACKGROUND

The lipid accumulation product (LAP) index is an abdominal adiposity marker.

OBJECTIVE

The aim of this study was to describe the cardiovascular risk of primary healthcare users through the LAP index and correlate it with anthropometric and biochemical indicators.

DESIGN AND SETTING

Cross-sectional study in primary care units in a city in northeastern Brazil.

METHODS

The subjects responded to a structured questionnaire that contained questions about their sociodemographic condition, and then underwent an anthropometric nutritional assessment. The LAP index values were expressed as three degrees of cardiovascular risk intensity: high risk (above the 75th percentile), moderate risk (between the 25th and 75th percentiles) and low risk (below the 25th percentile).

RESULTS

The median LAP index was 52.5 cm.mmol/l (range: 28.2-86.6), and there was no statistically significant difference between the sexes: 57.7 cm.mmol/l (24.5-91.1) and 49.5 cm.mmol/l (29.8-85.2) for females and males, respectively (P = 0.576). Among all the subjects, 67.2% were overweight and there was a statistically significant difference in mean LAP index between those who were and those who were not overweight. Statistically significant differences in anthropometric and biochemical markers for cardiovascular risk were observed among individuals who had higher LAP index values. There were significant correlations between the LAP index and all of the biochemical variables.

CONCLUSIONS

These significant correlations between the LAP index and the traditional biochemical risk markers may be useful within conventional clinical practice, for cardiovascular risk screening in primary healthcare.

摘要

背景

脂质蓄积产物(LAP)指数是一种腹部肥胖标志物。

目的

本研究旨在通过LAP指数描述基层医疗服务使用者的心血管风险,并将其与人体测量学和生化指标相关联。

设计与地点

在巴西东北部一个城市的基层医疗单位进行的横断面研究。

方法

受试者回答一份结构化问卷,其中包含有关其社会人口状况的问题,然后接受人体测量营养评估。LAP指数值表示为三个心血管风险强度等级:高风险(高于第75百分位数)、中度风险(在第25和第75百分位数之间)和低风险(低于第25百分位数)。

结果

LAP指数中位数为52.5 cm.mmol/l(范围:28.2 - 86.6),男女之间无统计学显著差异:女性为57.7 cm.mmol/l(24.5 - 91.1),男性为49.5 cm.mmol/l(29.8 - 85.2)(P = 0.576)。在所有受试者中,67.2%超重,超重者和未超重者的平均LAP指数存在统计学显著差异。LAP指数较高的个体在心血管风险的人体测量和生化标志物方面存在统计学显著差异。LAP指数与所有生化变量之间存在显著相关性。

结论

LAP指数与传统生化风险标志物之间的这些显著相关性在常规临床实践中可能有助于基层医疗中的心血管风险筛查。

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