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化疗引起的周围神经病变:与跌倒和受伤风险增加的关联。

Chemotherapy-Induced Peripheral Neuropathy: Association With Increased Risk of Falls and Injuries.

作者信息

Autissier Estelle

机构信息

Columbia University.

出版信息

Clin J Oncol Nurs. 2019 Aug 1;23(4):405-410. doi: 10.1188/19.CJON.405-410.

Abstract

BACKGROUND

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and degenerative side effect of many commonly used chemotherapy agents. Symptoms manifest as sensory and motor neuropathies. CIPN may necessitate chemotherapy dose reduction or discontinuation.

OBJECTIVES

This review intends to summarize literature linking CIPN to an increased risk of falls and injuries and provides recommendations to help maintain patient safety and maximize physical function.

METHODS

A literature search was conducted using MEDLINE®, PubMed®, and ScienceDirect.

FINDINGS

Assessment of CIPN and CIPN-related falls and injuries is vital in preventing related complications, and proper education of oncology nursing staff on CIPN assessment and management is necessary.

摘要

背景

化疗引起的周围神经病变(CIPN)是许多常用化疗药物导致的一种使人衰弱的退行性副作用。症状表现为感觉和运动神经病变。CIPN可能需要减少化疗剂量或停药。

目的

本综述旨在总结将CIPN与跌倒和受伤风险增加联系起来的文献,并提供有助于维持患者安全和最大化身体功能的建议。

方法

使用医学文献数据库(MEDLINE®)、美国国立医学图书馆生物医学数据库(PubMed®)和科学Direct数据库进行文献检索。

结果

评估CIPN以及与CIPN相关的跌倒和受伤对于预防相关并发症至关重要,并且有必要对肿瘤护理人员进行关于CIPN评估和管理的适当教育。

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