多种组合食物不耐受检测的临床应用价值

The Clinical Application Value of Multiple Combination Food Intolerance Testing.

作者信息

Lin Shudong, Yang Xiujing, Xing Ying, Wang Xingye, Li Yadong

机构信息

Clinical Laboratory, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, P.R. China.

出版信息

Iran J Public Health. 2019 Jun;48(6):1068-1073.

PMID:31341848

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635325/

Abstract

BACKGROUND

We aimed to investigate the clinical value of detecting 14 food intolerances.

METHODS

A total of 312 patients with food intolerance enrolled in the Third Affiliated Hospital of Qiqihar Medical University (Qiqihar, China) from Feb 2016 to Feb 2017 were selected. ELISA was used to detect intolerance specific IgG antibodies for 14 foods (pork, chicken, beef, shrimp, fish, crab, egg white/yolk, tomato, mushroom, milk, corn, rice, soybean, wheat).

RESULTS

The highest average positive rate of the patients was 42.31% for the crab, followed by shrimp 21.15%, egg white/yolk 18.27% and milk 16.99%. The positive rate from high to low was crab, shrimp, egg white/yolk, milk, fish, corn, soybeans, tomatoes, rice, mushrooms, wheat, pork, beef, chicken. There were significant differences in the specific IgG antibody positive rates between shrimp, soybean and wheat in the skin symptoms group, gastrointestinal symptoms group, respiratory symptom group and nervous system symptom group (<0.05). There was a significant difference in the positive rate of specific IgG antibodies between shrimp, crab and egg white/yolk in the adolescent group, the middle-aged group and the elderly group (<0.05).

CONCLUSION

The detection of food-specific IgG antibodies can help to determine which food intolerance caused the disease, and then adopt a fasting or diet method to avoid eating unsuitable foods and continually damaging the body, thus maintaining good health. The detection method provides a new idea for the diagnosis and prevention of diseases.

摘要

背景

我们旨在研究检测14种食物不耐受的临床价值。

方法

选取2016年2月至2017年2月在齐齐哈尔医学院第三附属医院（中国齐齐哈尔）登记的312例食物不耐受患者。采用酶联免疫吸附测定法（ELISA）检测14种食物（猪肉、鸡肉、牛肉、虾、鱼、蟹、蛋清/蛋黄、番茄、蘑菇、牛奶、玉米、大米、大豆、小麦）的不耐受特异性IgG抗体。

结果

患者中平均阳性率最高的是蟹，为42.31%，其次是虾21.15%、蛋清/蛋黄18.27%、牛奶16.99%。阳性率从高到低依次为蟹、虾、蛋清/蛋黄、牛奶、鱼、玉米、大豆、番茄、大米、蘑菇、小麦、猪肉、牛肉、鸡肉。皮肤症状组、胃肠道症状组、呼吸道症状组和神经系统症状组中，虾、大豆和小麦的特异性IgG抗体阳性率存在显著差异（<0.05）。青少年组、中年组和老年组中，虾、蟹和蛋清/蛋黄的特异性IgG抗体阳性率存在显著差异（<0.05）。