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妊娠与垂体瘤。

Pituitary Tumors in Pregnancy.

机构信息

Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Suite 530, Chicago, IL 60611, USA.

Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Suite 530, Chicago, IL 60611, USA.

出版信息

Endocrinol Metab Clin North Am. 2019 Sep;48(3):569-581. doi: 10.1016/j.ecl.2019.05.004. Epub 2019 Jun 13.

Abstract

Pituitary adenomas are common. The impact of pituitary tumors on fertility are mainly caused by oversecretion and/or undersecretion of pituitary hormones or compression of pituitary stalk and normal pituitary tissue by the tumor. Diagnosing and managing pituitary tumors during pregnancy involve many challenges, including the effect of hormone excess or deficiency on pregnancy outcome, changes in the pituitary or pituitary-related hormones, changes in tumor size, and the impact of various treatments of pituitary tumors on maternal and fetal outcomes. This article discusses the diagnosis and treatment of patients with prolactinomas, acromegaly, Cushing disease, and other pituitary tumors during pregnancy.

摘要

垂体腺瘤很常见。垂体肿瘤对生育能力的影响主要是由于垂体激素的过度分泌和/或分泌不足,或者肿瘤对垂体柄和正常垂体组织的压迫所致。在怀孕期间诊断和治疗垂体肿瘤涉及许多挑战,包括激素过多或不足对妊娠结局的影响、垂体或垂体相关激素的变化、肿瘤大小的变化,以及各种垂体肿瘤治疗方法对母儿结局的影响。本文讨论了妊娠期间催乳素瘤、肢端肥大症、库欣病和其他垂体肿瘤患者的诊断和治疗。

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