Pelvic Floor Unit, Department of Surgery, Aarhus University Hospital, Aarhus N, Denmark.
Pelvic Floor Unit, Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus N, Denmark.
Colorectal Dis. 2020 Jan;22(1):71-79. doi: 10.1111/codi.14792. Epub 2019 Sep 3.
Secondary sphincter repair has been the conventional management of anal incontinence (AI) when a structural defect in the sphincter is recognized. However, disappointing long-term results have contributed to a tendency towards an increasing use of alternative treatment methods. This study aimed to assess the long-term functional outcomes following a secondary sphincter repair in women with AI after obstetric sphincter injury.
This is a questionnaire study of women who underwent a secondary sphincter repair in Denmark between January 1990 and December 2005. Patients were identified through the Danish National Patient Registry. Functional outcomes were assessed by a self-administered questionnaire in 2010 and 2018. Primary outcomes were Wexner and St. Mark's scores. Impact on quality of life was assessed using the Fecal Incontinence Quality of Life Scale.
Functional outcome was assessed in 370 women in 2010 and 255 women in 2018. At 18.3 [interquartile range (IQR 15.0-22.0)] years of follow-up, the mean ± SD Wexner score was 8.8 ± 4.8 and the mean St. Mark's score was 11.7 ± 5.0. Flatus incontinence was the most frequent symptom, reported by 97%. Incontinence for liquid and solid stools was reported by 75% and 54%, respectively. There were no significant changes in incontinence frequencies over time. Women with a Wexner score of ≥ 9 had a significantly lower quality of life score in all domains than did women with a Wexner score of < 9 (P < 0.001).
At long-term follow-up, few patients are fully continent following a secondary sphincter repair. However, it appears that the functional results remain stable at very long-term follow-up.
当识别到括约肌的结构缺陷时,二级括约肌修复一直是肛门失禁(AI)的常规治疗方法。然而,令人失望的长期结果导致人们越来越倾向于使用替代治疗方法。本研究旨在评估产科括约肌损伤后 AI 女性接受二级括约肌修复后的长期功能结果。
这是一项在丹麦于 1990 年 1 月至 2005 年 12 月期间接受二级括约肌修复的女性患者的问卷调查研究。通过丹麦国家患者登记处识别患者。2010 年和 2018 年通过自我管理问卷评估功能结果。主要结局指标是 Wexner 和 St. Mark 评分。使用粪便失禁生活质量量表评估对生活质量的影响。
2010 年评估了 370 名女性的功能结果,2018 年评估了 255 名女性。在 18.3 岁[四分位距(IQR 15.0-22.0)]的随访中,平均±SD Wexner 评分分别为 8.8±4.8 和 11.7±5.0。St. Mark 评分。气体失禁是最常见的症状,有 97%的患者报告了这种症状。分别有 75%和 54%的患者报告了液体和固体粪便失禁。随着时间的推移,失禁频率没有明显变化。Wexner 评分≥9 的女性在所有领域的生活质量评分均明显低于 Wexner 评分<9 的女性(P<0.001)。
在长期随访中,很少有患者在接受二级括约肌修复后完全无失禁。然而,在非常长期的随访中,功能结果似乎仍然稳定。