A possible consequence of long-term elimination diet in IgE mediated subclinical food hypersensitivity.

IgE-mediated sub-clinical food hypersensitivity is recognized, but the hypersensitivity indicated is not always in accord with the observed symptoms. Study of 2 cases shows the inefficacy of a prescribed exclusion diet, without confirmation of the relationship between symptomatology and the food allergy. In addition, elimination of the foods aggravated the sensitivity of the patients and symptoms after provocation tests. Further studies must be made to decide whether there is a sound basis for long-term exclusion diets in sub-clinical food hypersensitivity.