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生物陶瓷:从骨替代物到用于药物递送的纳米颗粒

Bioceramics: from bone substitutes to nanoparticles for drug delivery.

作者信息

Vallet-Regí María

机构信息

Instituto de Investigación Sanitaria Hospital 12 de Octubre i + 12, Plaza Ramón y Cajal s/n, E-28040, Madrid, Spain; and Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain.

出版信息

Pure Appl Chem. 2019 Apr;91(4):687-706. doi: 10.1515/pac-2018-0505. Epub 2019 Jan 29.

Abstract

Since the second half of the 20 century, bioceramics are used for bone repair and regeneration. Inspired by bones and teeth, and aimed at mimicking their structure and composition, several artificial bioceramics were developed for biomedical applications. And nowadays, in the 21 century, with the increasing prominence of nanoscience and nanotechnology, certain bioceramics are being used to build smart drug delivery systems, among other applications. This minireview will mainly describe both tendencies through the research work carried out by the research team of María Vallet-Regí.

摘要

自20世纪下半叶以来,生物陶瓷被用于骨修复和再生。受骨骼和牙齿的启发,并旨在模仿它们的结构和组成,人们开发了几种用于生物医学应用的人造生物陶瓷。如今,在21世纪,随着纳米科学和纳米技术的日益突出,某些生物陶瓷正被用于构建智能药物递送系统以及其他应用。本综述将主要通过玛丽亚·瓦列特-雷吉研究团队开展的研究工作来描述这两种趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f24c/6675605/542ef4267c6a/EMS83668-f001.jpg

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