Department of Neurosurgery, Haukeland University Hospital, NO-5021, Bergen, Norway.
Department of Clinical Medicine K1, University of Bergen, PB 7804, NO-5020, Bergen, Norway.
Acta Neurochir (Wien). 2019 Nov;161(11):2253-2263. doi: 10.1007/s00701-019-03990-6. Epub 2019 Aug 5.
In a previous study, we reported a short-term (6 months) postoperative improvement of health-related quality of life (Qol) in patients operated for an arachnoid cyst (AC). The aim was to investigate whether this initial improvement was permanent.
A long-term (5 ± 2 years) prospective study comparing Qol and complaints before and 5 ± 2 years after surgical fenestration for AC in 76 adult patients, using the Short Form 36 (SF-36) scores, Glasgow Benefit Inventory (GBI) questionnaires, and Visual Analogue Scales (VAS) for headache and dizziness, similarly to what they did at short-term follow-up.
At short-term and long-term follow-ups, 73.4% and 82%, respectively, of the patients were better from their headache compared with preoperative scores. The corresponding improvement rates for dizziness were 61.7% (short-term) and 67.9 (long-term). Preoperatively, the mean headache VAS score was 45.6; at short-term follow-up, this was reduced to 25.7, and at long-term follow-up, this further reduced to 24.8. The preoperative mean VAS score for dizziness (35.2) was reduced to 12.2 (short-term) and 13.9 (long-term). The significant postoperative improvement of patient-reported Qol at short-term follow-up remained at long-term follow-up across seven out of eight SF-36 dimensions and three out of four GBI subscale scores. Similar to at short-term follow-up, the Qol improvement is correlated to improvement in headache and/or dizziness.
The previously reported postoperative, short-term improvement in Qol and complaints appears stable, as the improvement remains at long-term follow-up. This suggests that the beneficial effects of surgical treatment are long-lasting.
在之前的研究中,我们报告了蛛网膜囊肿(AC)患者术后短期(6 个月)健康相关生活质量(Qol)的改善。目的是研究这种初步改善是否持久。
一项长期(5±2 年)前瞻性研究,比较了 76 例成年患者接受蛛网膜囊肿开窗术后 5±2 年的 Qol 和术前、术后的抱怨,使用简明 36 项健康调查量表(SF-36)评分、格拉斯哥获益量表(GBI)问卷和视觉模拟量表(VAS)评估头痛和头晕,与短期随访时的评估方法类似。
在短期和长期随访时,分别有 73.4%和 82%的患者的头痛比术前评分有所改善。头晕的相应改善率分别为 61.7%(短期)和 67.9%(长期)。术前头痛 VAS 评分平均为 45.6;短期随访时降至 25.7,长期随访时进一步降至 24.8。术前头晕 VAS 评分平均为 35.2,短期随访时降至 12.2,长期随访时降至 13.9。在 8 个 SF-36 维度中有 7 个和 4 个 GBI 亚量表中有 3 个在短期随访时显著改善的患者报告 Qol 在长期随访时仍保持改善。与短期随访时一样,Qol 的改善与头痛和/或头晕的改善相关。
之前报告的术后短期 Qol 和抱怨的改善似乎是稳定的,因为这种改善在长期随访时仍存在。这表明手术治疗的有益效果是持久的。