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高血压性脉络膜病变中的双侧巨大视网膜色素上皮撕裂

Bilateral giant retinal pigment epithelial tears in hypertensive choroidopathy.

作者信息

Matsubara Natsuki, Kato Aki, Kominami Aoi, Nozaki Miho, Yasukawa Tsutomu, Yoshida Munenori, Ogura Yuichiro

机构信息

Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.

出版信息

Am J Ophthalmol Case Rep. 2019 Jul 24;15:100525. doi: 10.1016/j.ajoc.2019.100525. eCollection 2019 Sep.

Abstract

PURPOSE

To report a case of hypertensive choroidopathy with bilateral bullous serous retinal detachments (SRDs), retinal pigment epithelial detachments (PEDs), and giant retinal pigment epithelial (RPE) tears.

OBSERVATIONS

A 68-year-old man with a history of hypertension and diabetes mellitus presented with bilateral visual loss of about 10 day's duration. He discontinued his oral medications for 2 months without the advice of a physician. At his first visit, the best-corrected visual acuities (BCVAs) were 0.02 in the right eye and 0.3 in the left eye (decimal notation), and the respective intraocular pressures were 15 and 13 mmHg. Bullous SRDs, large PEDs, and giant RPE tears were present bilaterally. Blot retinal hemorrhages and hard exudates were seen in the left eye. The systemic blood pressure was 231/77 mmHg, and bilateral lower leg edema was observed. Biochemical blood tests showed deteriorated renal function, hypoalbuminemia, and hyperglycemia. Ultra-wide-field fundus fluorescein angiography showed leakage at the areas of the SRDs and hyperfluorescent areas corresponding to the RPE tears bilaterally. Indocyanine green angiography showed hypofluorescent areas corresponding to the PEDs. Systemic computed tomography and magnetic resonance imaging were performed, and no malignancy was found. Based on these findings, hypertensive choroidopathy was diagnosed. A week after antihypertensive treatment, the SRDs and PEDs resolved bilaterally, and the BCVAs improved to 0.4 and 0.5 in the right and left eyes, respectively. The RPE tears remained in both eyes, although the SRDs and PEDs did not recur.

CONCLUSIONS AND IMPORTANCE

Hypertensive choroidopathy must be considered in the differential diagnosis of SRDs and/or PEDs.

摘要

目的

报告一例伴有双侧大泡性浆液性视网膜脱离(SRD)、视网膜色素上皮脱离(PED)和巨大视网膜色素上皮(RPE)撕裂的高血压性脉络膜病变。

观察结果

一名68岁男性,有高血压和糖尿病病史,出现双侧视力丧失约10天。他在未咨询医生的情况下停用口服药物2个月。首次就诊时,右眼最佳矫正视力(BCVA)为0.02,左眼为0.3(十进制表示),眼压分别为15和13 mmHg。双侧均存在大泡性SRD、大的PED和巨大RPE撕裂。左眼可见视网膜点状出血和硬性渗出。全身血压为231/77 mmHg,观察到双侧小腿水肿。血液生化检查显示肾功能恶化、低白蛋白血症和高血糖。超广角眼底荧光血管造影显示双侧SRD区域渗漏以及与RPE撕裂对应的高荧光区域。吲哚菁绿血管造影显示与PED对应的低荧光区域。进行了全身计算机断层扫描和磁共振成像,未发现恶性肿瘤。基于这些发现,诊断为高血压性脉络膜病变。抗高血压治疗一周后,双侧SRD和PED消退,右眼和左眼的BCVA分别提高到0.4和0.5。尽管SRD和PED未复发,但双眼的RPE撕裂仍然存在。

结论与意义

在鉴别诊断SRD和/或PED时必须考虑高血压性脉络膜病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6835/6675940/f6c1f9321b17/gr1.jpg

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