Leonard Conrad, Wood Scott, Holmes Oliver, Waddell Nic, Gorse Dominique, Hansen David P, Pearson John V
QIMR Berghofer Medical Research Institute, Brisbane, Australia.
QFAB Bioinformatics, Brisbane, Australia.
Stud Health Technol Inform. 2019 Aug 8;266:149-155. doi: 10.3233/SHTI190787.
Genomic testing is rapidly moving into healthcare practice. However it comes with informatics challenges that the healthcare system has not previously faced - the raw data can be hundreds of gigabytes per test, the compute demands can be thousands of CPU hours, and the test can reveal deeply private health-srelated information that can have implications for anyone related to the person tested. While not a panacea, cloud computing has particular properties that can ameliorate some of these difficulties. This paper presents some of the key lessons learned while deploying a set of genomic analyses on cloud computing for Queensland Genomics.