Tito Emmanuel, Knapp Blayne, Bucca Anthony, Espiridion Eduardo D
Internal Medicine, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Family Medicine, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Cureus. 2019 Jun 5;11(6):e4835. doi: 10.7759/cureus.4835.
Psychogenic nonepileptic seizures (PNES), historically referred to as pseudoseizures or hysterical seizures, are sudden disturbances of motor, sensory, autonomic, cognitive, or emotional functions that can mimic epileptic seizures. PNES have a psychologic etiology related to dissociative disorders or conversion disorders, as opposed to the abnormally excessive neuronal activity found in epileptic seizures. Psychosocial conflicts are essentially converted into physical symptoms, resulting in seizure-like symptoms. This case report presents a 42-year-old male with a past history of child abuse, drug abuse, schizoaffective disorder, prior psychiatric hospitalizations, and diabetes mellitus type 2 who was admitted to the behavioral health unit with recurrent seizure-like episodes. These episodes were witnessed in the ED, however, appropriate workup failed to confirm abnormal neural activity or evidence of any brain injury. The patient was admitted to the psychiatric service where he was monitored for additional epileptic activity using long-term video-electroencephalogram (EEG) monitoring (LT-VEEG). While subsequent clinical events that resembled epileptic seizures were observed, the LT-VEEG failed to identify any epileptic activity. A diagnosis of PNES was established and a decision was made for the patient to remain on his current antiepileptic, psychiatric, and diabetes medications during his hospitalization. He showed gradual improvement during his stay and confirmed an understanding of his diagnosis. He was released three days later with instructions for follow-up and continued treatment with his outpatient psychiatrist. Early therapeutic counseling in patients who have a differential diagnosis of PNES should be considered to help identify and address the underlying causes of the seizure activity in an effort to curtail these seizure-like events.
心因性非癫痫性发作(PNES),历史上曾被称为假性发作或癔症性发作,是运动、感觉、自主神经、认知或情感功能的突然紊乱,可模仿癫痫发作。与癫痫发作中发现的异常过度神经元活动不同,PNES具有与分离性障碍或转换性障碍相关的心理病因。心理社会冲突本质上转化为身体症状,导致类似发作的症状。本病例报告介绍了一名42岁男性,有儿童期受虐、药物滥用、精神分裂症情感障碍、既往精神病住院史以及2型糖尿病史,因反复出现类似发作的情况入住行为健康科。这些发作在急诊科被观察到,然而,适当的检查未能证实异常神经活动或任何脑损伤的证据。患者被收治到精神科,在那里使用长期视频脑电图(EEG)监测(LT-VEEG)对其进行额外的癫痫活动监测。虽然观察到了随后类似癫痫发作的临床事件,但LT-VEEG未能识别出任何癫痫活动。确诊为PNES,并决定让患者在住院期间继续服用目前的抗癫痫药、精神科药物和糖尿病药物。他在住院期间逐渐好转,并确认理解了自己的诊断。三天后他出院了,带着随访指示,并继续接受门诊精神科医生的治疗。对于有PNES鉴别诊断的患者,应考虑早期进行治疗咨询,以帮助识别和解决发作活动的潜在原因,从而减少这些类似发作的事件。