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模拟肺恶性肿瘤的局灶性机化性肺炎:用泼尼松龙治疗。

Focal organizing pneumonia simulating lung malignancy: treated with prednisolone.

作者信息

Kilaru Hemanth, Jalna Mohd Vaseem, Kilaru Satish Chandra, Nandury Eshwar Chandra, Khan Mohammed Zia Ur Rehman

机构信息

Pulmonology Prathima Institute of Medical Sciences Karimnagar India.

Radiology Virinchi Hospitals Hyderabad India.

出版信息

Respirol Case Rep. 2019 Aug 5;7(7):e00469. doi: 10.1002/rcr2.469. eCollection 2019 Oct.

Abstract

Focal cryptogenic organizing pneumonia (FOP) is a localized form of cryptogenic organizing pneumonia (COP). It is an uncommon clinicopathological entity associated with non-specific symptoms and radiographic findings simulating lung malignancy. Incidence of idiopathic FOP is not known and only reported as case series. Its treatment usually involved surgical resection. Here, we report a case of a 62-year-old female presenting with a history of dyspnoea, persistent paroxysms of dry cough, and low-grade fever of three weeks duration with a solitary consolidation on imaging. Computed tomography-guided biopsy showed an organizing pneumonia pattern. A therapeutic trial with prednisolone resulted in resolution without the need for surgical resection, without recurrence after follow-up for 12 months.

摘要

局灶性隐源性机化性肺炎(FOP)是隐源性机化性肺炎(COP)的一种局限性形式。它是一种罕见的临床病理实体,伴有非特异性症状和类似肺恶性肿瘤的影像学表现。特发性FOP的发病率尚不清楚,仅作为病例系列报道。其治疗通常涉及手术切除。在此,我们报告一例62岁女性病例,患者有呼吸困难、持续阵发性干咳病史,低热3周,影像学显示单发实变。计算机断层扫描引导下活检显示为机化性肺炎模式。泼尼松龙治疗试验使病情缓解,无需手术切除,随访12个月无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bf0/6682542/29121c878f86/RCR2-7-e00469-g001.jpg

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