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空气流化疗法治疗严重烧伤:来自奥地利烧伤重症监护病房的回顾性研究。

Air-fluidized therapy in the treatment of severe burns: A retrospective study from a burn intensive care unit in Austria.

机构信息

Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Austria.

Research Office (Biostatistics), Paracelsus Medical University Salzburg, Austria; Department of Ophthalmology and Optometry, Paracelsus Medical University Salzburg, Austria.

出版信息

Burns. 2020 Feb;46(1):136-142. doi: 10.1016/j.burns.2019.07.026. Epub 2019 Aug 14.

Abstract

INTRODUCTION

Air-fluidized therapy (AFT) has long been used in the treatment of severe burns. In patients with extensive burns involving the posterior trunk, we aim to keep affected posterior areas dry and to postpone their treatment, initially applying available split-thickness skin grafts in functionally more important regions. We retrospectively assessed the impact of AFT on the survival of patients treated in the burn intensive care unit (ICU) of the Medical University of Vienna, Austria, between 2003 and 2016.

METHODS

This retrospective single-center study included patients aged ≥18 years with burned total body surface area (TBSA) ≥20% and IIb-III° thermal injuries on the posterior trunk who received AFT. Survival rates were compared with those predicted by the abbreviated burn severity index (ABSI). Demographic, clinical, and surgical data were analyzed.

RESULTS

Seventy-five of 110 patients with posterior trunk burns received AFT. Their survival rate exceeded that predicted by the ABSI score (mean ABSI, 10.0 ± 2.0; 73.3% (95% CI: 62-83%) survival rate vs. 20-40% predicted; p <  0.0001); no such difference was observed in the non-AFT group (mean, 8.8 ± 1.9; 65.7% (95% CI: 48-81%) survival rate vs. 50-70% predicted). Patients receiving AFT had significantly greater TBSA (median, 50% (35-60) vs. 30% (25-45) and longer ICU stays (median, 63 (36-92) vs. 18 (9-52) days; both p <  0.0001). Fifty-one (68.0%) patients in the AFT group and 26 (74.3%) patients in the non-AFT group underwent posterior trunk surgery (p =  0.66) a median of 16 (10-26) and 5 (2.5-9.5) days, respectively, after admission (p <  0.0001).

CONCLUSIONS

Patients receiving AFT had significantly better survival than predicted by ABSI score in contrast to patients not receiving AFT although burn injuries in this group were more severe (greater TBSA, higher ABSI). As intensive care was similar in these groups aside from AFT, the better survival could be attributed to this additional therapy.

摘要

简介

空气流化疗法(AFT)长期以来一直用于治疗严重烧伤。对于广泛烧伤涉及后躯干的患者,我们的目标是保持受影响的后区域干燥,并推迟治疗,最初在功能上更重要的区域应用现有的部分厚度皮肤移植。我们回顾性评估了 2003 年至 2016 年期间在奥地利维也纳医科大学烧伤重症监护病房(ICU)接受 AFT 治疗的患者的生存情况。

方法

这项回顾性单中心研究包括年龄≥18 岁、烧伤总面积(TBSA)≥20%和后躯干 IIb-III°热损伤的患者,他们接受了 AFT。将生存率与简化烧伤严重程度指数(ABSI)预测的生存率进行比较。分析了人口统计学、临床和手术数据。

结果

110 例后躯干烧伤患者中有 75 例接受了 AFT。他们的生存率高于 ABSI 评分预测值(平均 ABSI,10.0±2.0;73.3%(95%CI:62-83%)生存率与 20-40%预测值相比;p<0.0001);在未接受 AFT 的组中未观察到这种差异(平均,8.8±1.9;65.7%(95%CI:48-81%)生存率与 50-70%预测值相比)。接受 AFT 的患者 TBSA 明显更大(中位数,50%(35-60)比 30%(25-45)),ICU 停留时间也更长(中位数,63(36-92)比 18(9-52)天;均 p<0.0001)。AFT 组中有 51(68.0%)例和非 AFT 组中有 26(74.3%)例患者接受了后躯干手术(p=0.66),入院后中位数分别为 16(10-26)和 5(2.5-9.5)天(p<0.0001)。

结论

与未接受 AFT 的患者相比,接受 AFT 的患者的生存率明显高于 ABSI 评分预测值,尽管该组烧伤更严重(更大的 TBSA,更高的 ABSI)。由于除 AFT 之外这些组的重症监护相同,因此更好的生存率可能归因于这种额外的治疗。

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