饮食摄入、心理困扰和胃肠道症状之间的关系：一项日记研究。
Relations between food intake, psychological distress, and gastrointestinal symptoms: A diary study.
机构信息
Department of Internal Medicine & Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Translational Research Centre for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Belgium.
出版信息
United European Gastroenterol J. 2019 Aug;7(7):965-973. doi: 10.1177/2050640619839859. Epub 2019 Mar 16.
BACKGROUND
Gastrointestinal symptoms can be triggered by food intake and psychological distress, but individual-level research on food-symptom and stress-symptom associations is scarce.
OBJECTIVE
We aimed to identify associations between food intake, psychological distress and gastrointestinal symptoms, and their implications for personalised clinical management.
METHODS
Through the mobile phone application , 163 users kept, for a median of five weeks, a diary of food intake, psychological distress and gastrointestinal symptoms. We quantified associations between these on the individual level. The presence of individual-level associations was compared over latent classes of daily symptom patterns.
RESULTS
Various gastrointestinal symptoms had demonstrable food-symptom associations (heartburn: 73%, discomfort: 67%, diarrhoea: 57%, bloating: 53%, and gas: 48%). Food-symptom associations for pain in the abdomen (33%) were concentrated in the latent class of individuals with pain in the morning (68%), rather than those with pain in the evening and night (27% and 10%, respectively, < 0.001). Stress-symptom relations were also found, although only 18% of individuals reported psychological distress.
CONCLUSION
Personal food-symptom and stress-symptom relations can be detected, and may translate into specific daily symptom patterns. A next step will be to let personal food-symptom and stress-symptom relations serve as the basis for personalised clinical management.
背景
胃肠道症状可能由食物摄入和心理困扰引发，但针对食物症状和压力症状关联的个体水平研究较为匮乏。
目的
我们旨在确定食物摄入、心理困扰和胃肠道症状之间的关联，并探讨其对个性化临床管理的意义。
方法
通过手机应用程序，163 名用户记录了食物摄入、心理困扰和胃肠道症状的日记，中位时间为五周。我们在个体水平上量化了这些关联。在每日症状模式的潜在类别中比较了个体水平关联的存在情况。
结果
各种胃肠道症状都表现出明显的食物症状关联（烧心：73%，不适：67%，腹泻：57%，腹胀：53%，气体：48%）。腹部疼痛的食物症状关联（33%）主要集中在早晨疼痛的潜在类别中（68%），而不是晚上和夜间疼痛的类别中（分别为 27%和 10%，<0.001）。也发现了压力症状的关联，但只有 18%的个体报告存在心理困扰。
结论
可以检测到个体的食物症状和压力症状关联，并可能转化为特定的每日症状模式。下一步将是让个体的食物症状和压力症状关联成为个性化临床管理的基础。
Zotero 插件