运动结合电疗法可增强一名青少年III型脊髓性肌萎缩症患者的运动功能。

Exercise Combined with Electrotherapy Enhances Motor Function in an Adolescent with Spinal Muscular Atrophy Type III.

作者信息

Gobbo Massimiliano, Lazzarini Sara, Vacchi Laura, Gaffurini Paolo, Bissolotti Luciano, Padovani Alessandro, Filosto Massimiliano

机构信息

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Laboratory of Clinical Integrative Physiology, University of Brescia, Brescia, Italy.

出版信息

Case Rep Neurol Med. 2019 Jul 22;2019:4839793. doi: 10.1155/2019/4839793. eCollection 2019.

DOI:10.1155/2019/4839793

PMID:31428487

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6679856/

Abstract

BACKGROUND

Electrotherapy is widely used in physical therapy to increase muscle mass, improve motor function, and assist physical activity in several neurologic conditions. However, concerning Spinal Muscular Atrophy (SMA), limited evidence exists on the role of electrotherapy as an adjunct for improving muscle strength and function.

CASE REPORT

An adolescent (13 y.o.) with SMA type III underwent an 18-week strengthening program divided into two stages. During Phase I (weeks: 1-8), a home-based program for quadriceps strengthening through neuromuscular electrical stimulation (NMES) was provided. In Phase II (weeks: 9-18), at-home NMES was combined with functional electrical stimulation (FES) assisting volitional cycling for a broader, systemic conditioning. The treatment improved patient's structural and functional motor outcomes (quadriceps circumference and strength, Tinetti scale, and Hammersmith scale) as well as independence in stair climbing.

CLINICAL REHABILITATION IMPACT

The purpose of this report is to raise awareness of the potential role of electrotherapy to help improving motor performance in SMA patients and, secondly, to foster further research aimed at assessing the actual contribution this intervention may have as an add-on therapy to existing care.

摘要

背景

电疗法在物理治疗中被广泛应用，以增加肌肉量、改善运动功能，并在多种神经系统疾病中辅助身体活动。然而，关于脊髓性肌萎缩症（SMA），电疗法作为改善肌肉力量和功能的辅助手段的作用，证据有限。

病例报告

一名13岁的III型SMA青少年患者接受了一个为期18周的强化训练计划，分为两个阶段。在第一阶段（第1 - 8周），提供了一个通过神经肌肉电刺激（NMES）在家中进行股四头肌强化训练的计划。在第二阶段（第9 - 18周），在家中进行的NMES与功能性电刺激（FES）相结合，辅助自主骑行，以进行更广泛的全身训练。该治疗改善了患者的结构和功能运动结果（股四头肌周长和力量、Tinetti量表和Hammersmith量表）以及爬楼梯的独立性。