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软骨-骨呼吸上皮腺样错构瘤(COREAH):病例报告及文献综述

Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma (COREAH): Case Report and Literature Review.

作者信息

Daniel Andrew, Wong Eugene, Ho Joyce, Singh Narinder

机构信息

Westmead Hospital, Westmead, NSW, Australia.

出版信息

Case Rep Otolaryngol. 2019 Jul 25;2019:5247091. doi: 10.1155/2019/5247091. eCollection 2019.

Abstract

Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is an extremely rare lesion of the nasal cavity with only 11 reported cases in the literature. COREAH is of interest as it may be easily mistaken for other diseases of the nasal cavity with higher morbidity, which require significantly different management strategies. We report, to the best of our knowledge, the oldest documented case of COREAH in the literature: an 83-year-old female who presented with headaches and was found to have a posterior nasal septal lesion. Uniquely, the patient had sequential scans performed 1 year apart demonstrating only minor interval growth. We describe our experience in managing a patient with COREAH and review the world literature, to better define aspects of the history, presentation, and investigations that may allow differentiation from more sinister disease.

摘要

软骨-骨化性呼吸上皮腺样错构瘤(COREAH)是鼻腔极为罕见的病变,文献中仅报道过11例。COREAH值得关注,因为它很容易被误诊为鼻腔其他发病率较高的疾病,而这些疾病需要截然不同的治疗策略。据我们所知,我们报告了文献中记录的最年长的COREAH病例:一名83岁女性,因头痛就诊,发现鼻中隔后部有病变。独特的是,该患者相隔1年进行了连续扫描,结果显示病变仅有轻微进展。我们描述了我们治疗一名COREAH患者的经验,并回顾了世界文献,以更好地明确病史、临床表现和检查方面的特征,从而有助于与更严重的疾病相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d28/6683791/a9f81c801beb/CRIOT2019-5247091.001.jpg

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