Department of Ophthalmology, Ente Ecclesiastico Ospedale Generale Regionale "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milan, Italy.
Ophthalmic Res. 2020;63(1):18-24. doi: 10.1159/000501561. Epub 2019 Aug 20.
To assess closure rate and visual outcome of a court of patients with macular hole (MH) who underwent surgical repair with intraoperative optical coherence tomography (iOCT)-confirmed MH closure and short-term postoperative face-down posturing (FDP). Secondary aim was to assess the correlation between iOCT and postoperative OCT at day 1.
Retrospective clinical study conducted in the Miulli Hospital Acquaviva delle Fonti (Italy), enrolling patients with idiopathic MH who underwent 25-G pars plana vitrectomy plus internal limiting membrane peeling. During surgery, closure of MH was confirmed by iOCT and short-term FDP (12-24 h, until day-1 visit) was prescribed. All patients had measurement of best-corrected visual acuity (BCVA) and spectral domain-OCT before the surgery and during follow-up (at 1 day, 1 month, 3 months).
Twenty-nine eyes of 29 patients (14 males, 62.1%) were enrolled in the study. MH mean size was 451.7 ± 139.7 µm and baseline BCVA was 0.77 ± 0.26 logarithm of the minimum angle of resolution (LogMAR). MH was confirmed to be closed in 100% of patients intraoperatively (iOCT) and at OCT during early follow-up (1-3 days). Mean time of FDP was 18 ± 2.6 h. At 3 months, MH closure rate was 93%; 2 eyes -underwent secondary MH repair surgery. Final BCVA was 0.39 ± 0.22 LogMAR (p < 0.0001).
iOCT-based confirmation of MH closure could be a safe and useful tool for prescribing short-term FDP after surgery, with high closure rate and no additional complication. The execution of an OCT in the immediate postoperative days could be potentially unnecessary.
评估接受术中光学相干断层扫描(iOCT)证实的黄斑裂孔(MH)闭合和短期术后面朝下体位(FDP)的 MH 患者的闭合率和视力结果。次要目的是评估 iOCT 与术后第 1 天 OCT 的相关性。
回顾性临床研究在意大利 Acquaviva delle Fonti 的 Miulli 医院进行,招募了接受 25-G 经睫状体平坦部玻璃体切除术联合内界膜剥除术的特发性 MH 患者。在手术过程中,通过 iOCT 确认 MH 闭合,并规定短期 FDP(12-24 小时,直至第 1 天就诊)。所有患者在手术前和随访期间(第 1 天、1 个月、3 个月)均进行最佳矫正视力(BCVA)和光谱域-OCT 测量。
该研究纳入了 29 名患者(14 名男性,62.1%)的 29 只眼。MH 的平均大小为 451.7±139.7μm,基线 BCVA 为 0.77±0.26 最小角分辨率对数(LogMAR)。术中(iOCT)和早期随访期间(1-3 天),100%的患者 MH 均被证实闭合。FDP 的平均时间为 18±2.6 小时。3 个月时,MH 闭合率为 93%;2 只眼接受了二次 MH 修复手术。最终 BCVA 为 0.39±0.22 LogMAR(p<0.0001)。
基于 iOCT 的 MH 闭合确认可以作为术后短期 FDP 的安全有效工具,具有较高的闭合率且无额外并发症。术后早期进行 OCT 检查可能是不必要的。