Divisao de Cirurgia Geral e Trauma, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Clinics (Sao Paulo). 2019;74:e1074. doi: 10.6061/clinics/2019/e1074. Epub 2019 Aug 19.
Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis.
A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected.
Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality.
Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.
结直肠癌是最常见的恶性肿瘤之一。年龄是该病的一个危险因素,75%的病例发生在 65 岁以上的患者中。超过三分之一的病例存在梗阻、出血和穿孔等并发症,需要紧急治疗。我们旨在分析接受复杂结直肠癌手术的老年患者的特征,并评估与短期预后较差相关的因素。
对接受紧急手术治疗的复杂结直肠癌患者进行回顾性分析。收集人口统计学、临床、影像学和组织学数据。
分析了 67 例患者。中位年龄为 72 岁,近一半(46%)患者为女性。梗阻是最初表现中最常见的并发症(72%)。最常见的肿瘤部位是 22 例(32.8%)左半结肠和乙状结肠,17 例(25.4%)右半结肠。88%的病例进行了切除术,近一半的病例进行了一期吻合术。最常见的临床分期为 II 期(48%)和 III 期(22%)。43 例(65.7%)患者发生某种形式的术后并发症。Clavien-Dindo 分级 1、2 和 4 最为常见。80%的病例观察到完全肿瘤切除。30 天死亡率为 10.4%。高龄与更高的发病率和死亡率相关。
接受紧急手术治疗的复杂结直肠癌老年患者发病率和死亡率较高。高龄与较差的预后显著相关。