Wei Yunbo, Wang Minjie, Zhao Danyang, Li Hongxia
School of Mechanical Engineering, Dalian University of Technology, Dalian, Liaoning 116024, P.R.China.
School of Mechanical Engineering, Dalian University of Technology, Dalian, Liaoning 116024,
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2019 Aug 25;36(4):604-612. doi: 10.7507/1001-5515.201812009.
experimental test for mechanical properties of a vascular stent is a main method to evaluate its effectiveness and safety, which is of great significance to the clinical applications. In this study, a comparative study of planar, V-groove and radial compression methods for the radial support property test were performed, and the effects of compression rate and circumferential position on the test results were conducted. Based on the three-point bending method, the influences of compression rate and circumferential position on flexibility were also explored. And then a best test proposal was selected to evaluate the radial support property and flexibility of the three self-designed stents and the comparative biodegradable vascular stent (BVS) (BVS1.1, Abbott Vascular, USA) with different outside diameters of 1.4 mm, 1.7 mm and 2.4 mm. The results show that the developing trends of the compression load with the compression displacement measured by the three radial support property test methods are the same, but normalized radial force values are quite different. The planar compression method is more suitable for comparing the radial support properties of stents with different diameters and structures. Compression rate has no obvious effect on the testing results of both the radial support property and flexibility. Compression circumferential position has a great impact on testing radial support property with the planar or V-groove compression methods and testing flexibility with three-point bending method. The radial support properties of all the three self-designed stents are improved at a certain degree compared to that of the BVS stent. The study has better guide significance and reference value for testing mechanical properties of vascular stents.
血管支架力学性能的实验测试是评估其有效性和安全性的主要方法,对临床应用具有重要意义。本研究对平面、V型槽和径向压缩方法在径向支撑性能测试方面进行了对比研究,并探讨了压缩速率和圆周位置对测试结果的影响。基于三点弯曲法,还探究了压缩速率和圆周位置对柔韧性的影响。然后选择最佳测试方案来评估三种自行设计的不同外径(1.4毫米、1.7毫米和2.4毫米)的支架以及对比性可生物降解血管支架(BVS)(BVS1.1,美国雅培血管公司)的径向支撑性能和柔韧性。结果表明,三种径向支撑性能测试方法测得的压缩载荷随压缩位移的变化趋势相同,但归一化径向力值差异较大。平面压缩方法更适合比较不同直径和结构的支架的径向支撑性能。压缩速率对径向支撑性能和柔韧性的测试结果均无明显影响。压缩圆周位置对平面或V型槽压缩方法测试径向支撑性能以及三点弯曲法测试柔韧性有很大影响。与BVS支架相比,三种自行设计的支架的径向支撑性能均有一定程度的提高。该研究对血管支架力学性能测试具有较好的指导意义和参考价值。